Aims: Donation after circulatory death (DCD) could improve cardiac graft availability, which
is currently insufficient to meet transplant demand. However, DCD organs undergo an …

Background During donation after circulatory death (DCD), cardiac grafts are exposed to
potentially damaging conditions that can impact their quality and post-transplantation …

Introduction: The number of organs available for heart and lung transplantation is far short of
the number that is needed to meet demand. Perfusion and ventilation of donor organs after …

Gene-targeted therapy with the inotropic Ca2+-sensor protein S100A1 rescues contractile
function in post-ischemic heart failure and is being developed towards clinical trials. Its …

Background. Donation after circulatory death (DCD) heart transplantation (HTx) significantly
expands the donor pool and reduces waitlist mortality. However, high-level evidence-based …

Insufficient supply of cardiac grafts represents a severe obstacle in heart transplantation.
Donation after circulatory death (DCD), in addition to conventional donation after brain …

Rationale Donation after circulatory death (DCD) could improve cardiac graft availability.
However, strategies to optimize cardiac graft recovery remain to be established in DCD; …

Heart transplantation is facing a shortage of grafts. Donation after Circulatory Death (DCD)
would constitute a new potential of available organs. In the present work, we aimed to …

Oxidative stress occurs during ex-situ heart perfusion (ESHP) and may negatively affect
functional preservation of the heart. We sought to assess the status of key antioxidant …

Background Use of cardiac grafts obtained with donation after circulatory death (DCD) could
significantly improve donor heart availability. As DCD hearts undergo potentially deleterious …