[HTML][HTML] G2M checkpoint pathway alone is associated with drug response and survival among cell proliferation-related pathways in pancreatic cancer
Given the severe side effects of the treatments and poor survival, prognostic and predictive
biomarkers to guide management of pancreatic cancer are in critical need. We hypothesized …
biomarkers to guide management of pancreatic cancer are in critical need. We hypothesized …
[HTML][HTML] Clinical relevance of stem cell surface markers CD133, CD24, and CD44 in colorectal cancer
Colon cancer stem cells (CSC) identified by cell surface markers CD133, CD24, and CD44,
have been shown to be involved with tumor formation, chemotherapy resistance, and the …
have been shown to be involved with tumor formation, chemotherapy resistance, and the …
Abundance of reactive oxygen species (ROS) is associated with tumor aggressiveness, immune response, and worse survival in breast cancer
Purpose Reactive oxygen species (ROS) are oxygen-containing molecules that have high
reactivity and play roles in protection or harm the cancer cells. We aimed to clarify the …
reactivity and play roles in protection or harm the cancer cells. We aimed to clarify the …
Enhanced DNA repair pathway is associated with cell proliferation and worse survival in hepatocellular carcinoma (HCC)
Simple Summary We studied the relationship between enhancement of DNA repair and
cancer aggressiveness, tumor immune microenvironment, and patient survival in 749 …
cancer aggressiveness, tumor immune microenvironment, and patient survival in 749 …
Annexin A1 expression is associated with Epithelial–Mesenchymal Transition (EMT), cell proliferation, prognosis, and drug response in pancreatic cancer
Annexin A1 (ANXA1) is a calcium-dependent phospholipid-binding protein overexpressed
in pancreatic cancer (PC). ANXA1 expression has been shown to take part in a wide variety …
in pancreatic cancer (PC). ANXA1 expression has been shown to take part in a wide variety …
Enhanced immune response outperform aggressive cancer biology and is associated with better survival in triple-negative breast cancer
Although the value of tumor-infiltrating lymphocytes is well known, the clinical relevance of
an increased immune response, specifically in breast cancer, has not been investigated …
an increased immune response, specifically in breast cancer, has not been investigated …
Degree of early estrogen response predict survival after endocrine therapy in primary and metastatic ER-positive breast cancer
Simple Summary Over 70% of breast cancer patients in the US have estrogen receptor (ER)-
positive tumors. A better predictive biomarker of endocrine therapy would be useful to …
positive tumors. A better predictive biomarker of endocrine therapy would be useful to …
Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival
Cancer-associated adipocytes are known to cause inflammation; however, the role of
adipogenesis, the formation of adipocytes, in breast cancer is unclear. We hypothesized that …
adipogenesis, the formation of adipocytes, in breast cancer is unclear. We hypothesized that …
Viscoelastic stiffening of gelatin hydrogels for dynamic culture of pancreatic cancer spheroids
The tumor microenvironment (TME) in pancreatic adenocarcinoma (PDAC) is a complex
milieu of cellular and non-cellular components. Pancreatic cancer cells (PCC) and cancer …
milieu of cellular and non-cellular components. Pancreatic cancer cells (PCC) and cancer …
[HTML][HTML] Immune cytolytic activity is associated with reduced intra-tumoral genetic heterogeneity and with better clinical outcomes in triple negative breast cancer
Abstract Evaluation of the functional aspects if the tumor immune microenvironment (TIME),
such as the recently introduced cytolytic activity score (CYT) index have been under the …
such as the recently introduced cytolytic activity score (CYT) index have been under the …