Computed tomography angiography-derived fractional flow reserve (CT-FFR) for the detection of myocardial ischemia with invasive fractional flow reserve as …

B Zhuang, S Wang, S Zhao, M Lu - European radiology, 2020 - Springer
Objectives A method named computed tomography angiography-derived fractional flow
reserve (FFR CT) is an alternative method for detecting hemodynamically significant …

A test in context: fractional flow reserve: accuracy, prognostic implications, and limitations

A Jeremias, AJ Kirtane, GW Stone - Journal of the American College of …, 2017 - jacc.org
Fractional flow reserve (FFR) is an invasive procedure used during coronary angiography to
determine the functional significance of coronary stenoses. Its use is particularly helpful in …

Blinded physiological assessment of residual ischemia after successful angiographic percutaneous coronary intervention: the DEFINE PCI study

A Jeremias, JE Davies, A Maehara… - JACC: Cardiovascular …, 2019 - jacc.org
Objectives: This study sought to evaluate the incidence and causes of an abnormal
instantaneous wave-free ratio (iFR) after angiographically successful percutaneous …

[HTML][HTML] Validation of a three-dimensional quantitative coronary angiography-based software to calculate fractional flow reserve: the FAST study

K Masdjedi, LJC van Zandvoort… - …, 2020 - eurointervention.pcronline.com
Aims: The aim of this study was to validate novel software to calculate vessel fractional flow
reserve (vFFR) based on 3D-QCA and to assess inter-observer variability in patients who …

Accuracy of computational pressure-fluid dynamics applied to coronary angiography to derive fractional flow reserve: FLASH FFR

J Li, Y Gong, W Wang, Q Yang, B Liu, Y Lu… - Cardiovascular …, 2020 - academic.oup.com
Aims Conventional fractional flow reserve (FFR) is measured invasively using a coronary
guidewire equipped with a pressure sensor. A non-invasive derived FFR would eliminate …

1-Year outcomes of blinded physiological assessment of residual ischemia after successful PCI: DEFINE PCI trial

MR Patel, A Jeremias, A Maehara, M Matsumura… - Cardiovascular …, 2022 - jacc.org
Objectives The aim of this study was to identify the post–percutaneous coronary intervention
(PCI) target value of instantaneous wave-free ratio (iFR) that would best discriminate clinical …

CT fractional flow reserve: a practical guide to application, interpretation, and problem solving

P Rajiah, KW Cummings, E Williamson, PM Young - Radiographics, 2022 - pubs.rsna.org
CT fractional flow reserve (FFRCT) is a physiologic simulation technique that models
coronary flow from routine coronary CT angiography (CTA). To evaluate lesion-specific …

Diastolic pressure ratio: new approach and validation vs. the instantaneous wave-free ratio

NP Johnson, W Li, X Chen, B Hennigan… - European heart …, 2019 - academic.oup.com
Aims The instantaneous wave-free ratio (iFR) and whole-cycle Pd/Pa investigate coronary
physiology during non-hyperaemic conditions. To test for unique physiologic properties of …

Coronary angiography-derived index for assessing microcirculatory resistance in patients with non-obstructed vessels: The FLASH IMR study

D Huang, Y Gong, Y Fan, B Zheng, Z Lu, J Li… - American Heart …, 2023 - Elsevier
Background Assessing index of microcirculatory resistance (IMR) is customarily performed
using intracoronary wires fitted with sensors by at least 3 intracoronary injections of 3 to 4 …

Real world validation of the nonhyperemic index of coronary artery stenosis severity—resting full‐cycle ratio—RE‐VALIDATE

G Kumar, R Desai, A Gore, H Rahim… - Catheterization and …, 2020 - Wiley Online Library
Objective The primary objective was to demonstrate diagnostic equivalence between RFR
and iFR in clinical practice. Background The instantaneous wave‐free ratio (iFR), a …