Controlled drug delivery systems: current status and future directions

S Adepu, S Ramakrishna - Molecules, 2021 - mdpi.com
The drug delivery system enables the release of the active pharmaceutical ingredient to
achieve a desired therapeutic response. Conventional drug delivery systems (tablets …

Recent progress in nanostructured smart drug delivery systems for cancer therapy: a review

MI Khan, MI Hossain, MK Hossain… - ACS Applied Bio …, 2022 - ACS Publications
Traditional treatment approaches for cancer involve intravenous chemotherapy or other
forms of drug delivery. These therapeutic measures suffer from several limitations such as …

[HTML][HTML] On a highway to the brain: A review on nose-to-brain drug delivery using nanoparticles

ML Formica, DA Real, ML Picchio, E Catlin… - Applied Materials …, 2022 - Elsevier
The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …

Applications of metal-organic frameworks as drug delivery systems

B Maranescu, A Visa - International journal of molecular sciences, 2022 - mdpi.com
In the last decade, metal organic frameworks (MOFs) have shown great prospective as new
drug delivery systems (DDSs) due to their unique properties: these materials exhibit …

[HTML][HTML] Biosafety of mesoporous silica nanoparticles; towards clinical translation

A Lérida-Viso, A Estepa-Fernández… - Advanced Drug Delivery …, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …

[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers

TI Janjua, Y Cao, F Kleitz, M Linden, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …

Recent advances of chitosan-based nanoparticles for biomedical and biotechnological applications

Y Gao, Y Wu - International journal of biological macromolecules, 2022 - Elsevier
Chitosan is a natural alkaline polysaccharide, which widely exists in marine crustaceans
such as shrimp and crab, has been shown to have various biological activities. It has …

Biomedical applications of mesoporous silica nanoparticles as a drug delivery carrier

H Ahmed, SS Gomte, E Prathyusha… - Journal of Drug Delivery …, 2022 - Elsevier
Mesoporous silica nanoparticles (MSNs) attracted biomedical researchers due to their
unique properties like large surface area, pore-volume, and surface-active groups. These …

Effective adsorption of doxorubicin hydrochloride on zirconium metal-organic framework: equilibrium, kinetic and thermodynamic studies

GAA AlHazmi, KS AbouMelha, MG El-Desouky… - Journal of Molecular …, 2022 - Elsevier
Zirconium metal organic framework (Zr-MOF) has been synthesized by hydrothermal method
and various spectroscopic methods were used to characterize the samples. The adsorption …

Silica-based nanoparticles for biomedical applications: from nanocarriers to biomodulators

Y Yang, M Zhang, H Song, C Yu - Accounts of chemical research, 2020 - ACS Publications
Conspectus Silica-based nanoparticles (SNPs) are a classic type of material employed in
biomedical applications because of their excellent biocompatibility and tailorable …