DAA-mediated HCV cure reduces HIV DNA levels in HCV/HIV coinfected people

ST Gobran, A Pagliuzza, O Khedr, A Fert… - Journal of …, 2023 - Am Soc Microbiol
The human immunodeficiency virus (HIV) persists in HIV viral reservoirs despite
antiretroviral therapy (ART). Hepatitis C virus (HCV) coinfection is associated with increased …

Vedolizumab and ART in recent HIV-1 infection unveil the role of α4β7 in reservoir size

MR Jimenez-Leon, C Gasca-Capote, C Roca-Oporto… - JCI insight, 2024 - insight.jci.org
BACKGROUND. We evaluated the safety and viral rebound, after analytical treatment
interruption (ATI), of vedolizumab and ART in recent HIV-1 infection. We used this model to …

The HIV-1 reservoir landscape in persistent elite controllers and transient elite controllers

C Gasca-Capote, X Lian, C Gao… - The Journal of …, 2024 - Am Soc Clin Investig
BACKGROUND Persistent controllers (PCs) maintain antiretroviral-free HIV-1 control
indefinitely over time, while transient controllers (TCs) eventually lose virological control. It is …

[HTML][HTML] Long-term evolution in liver disease markers and immune and lipid profiles in vertically HIV/HCV-coinfected youths with sustained viral response after direct …

L Tarancon-Diez, I Carrasco, SJ de Ory… - Biomedicine & …, 2023 - Elsevier
This study aimed to analyse the long-term effect of direct-acting antivirals (DAAs) in vertically
acquired HIV/HCV-coinfected youths. We performed a multicentre, longitudinal and …

HIV-reservoir size is not affected either by HCV coinfection or by direct acting antivirals (DAAs) therapy

B Álvarez, MA Navarrete-Muñoz, V Briz… - Scientific Reports, 2022 - nature.com
The role of HCV on the HIV reservoir is controversial since the reduction on HIV-DNA levels
after HCV eradication with IFNα/RBV treatment seems to be the result of drugs instead of …

[HTML][HTML] The Era of DAAs: Assessing the Patients' Characteristics, Clinical Impact, and Emergence of Comorbidities in HIV/HCV-Coinfected versus HIV-Infected …

B Álvarez-Álvarez, L Prieto-Pérez… - Journal of Clinical …, 2024 - mdpi.com
Objective: To determine whether HIV-infected individuals versus individuals with HIV/HCV
coinfection, in the era of interferon-free therapies, exhibit an increased incidence of …

The Era of DAAs: Assessing the Clinical Impact and Emergence of Comorbidities in HIV/HCV-Coinfected versus HIV-Infected Individuals

B Álvarez-Álvarez, L Prieto-Pérez… - 2024 - researchsquare.com
Background Human immunodeficiency virus (HIV) infection causes sustained chronic
immune activation which is associated with earlier and more frequent onset of comorbidities …

[图书][B] The Impact of Direct-Acting Anti-Viral Therapy on Naïve CD4+ T Cell Lymphopenia and Cellular Immune Activation in HCV Infection and HCV/HIV Co-Infection

AWN Auma - 2021 - search.proquest.com
Individuals with hepatitis C virus (HCV) infection with or without antiretroviral therapy (ART)-
controlled HIV co-infection are commonly exposed to novel infections, and are at increased …

Identificação de um novo conjunto de biomarcadores para predição do curso da infecção pelo Mycobacterium tuberculosis

FT Lima - 2021 - teses.usp.br
O desenvolvimento de alternativas para conter a tuberculose (TB) aliado à necessidade de
ampla compreensão de mecanismos de ação da resposta imune à infecção impulsionam a …