[HTML][HTML] Advances in research into the mechanisms of Chinese Materia Medica against acute lung injury

Z Ding, R Zhong, T Xia, Y Yang, N Xing, W Wang… - Biomedicine & …, 2020 - Elsevier
Acute lung injury (ALI) is a common and serious disease. Numerous treatment options are
available but they do not improve quality of life or reduce mortality for ALI patients. Here, we …

[HTML][HTML] Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation

B Zhang, B Wang, S Cao… - … Journal of Molecular …, 2017 - spandidos-publications.com
Silybin is one of the main flavonoids produced by milk thistle, which has been used in the
treatment of liver diseases. In this study, we examined the protective effects and possible …

[HTML][HTML] MG53, a tissue repair protein with broad applications in regenerative medicine

Z Li, L Wang, H Yue, BA Whitson, E Haggard, X Xu… - Cells, 2021 - mdpi.com
Under natural conditions, injured cells can be repaired rapidly through inherent biological
processes. However, in the case of diabetes, cardiovascular disease, muscular dystrophy …

MiR-539-5p alleviates sepsis-induced acute lung injury by targeting ROCK1

L Meng, H Cao, C Wan, L Jiang - Folia Histochemica et …, 2019 - journals.viamedica.pl
Introduction. Sepsis-induced acute lung injury (ALI) is an inflammatory process involved with
simultaneous production of inflammatory cytokines and chemokines. In this study, we …

Role of microRNAs in Staphylococcus aureus infection: Potential biomarkers and mechanism

R Mirzaei, R Mohammadzadeh, H Mirzaei… - IUBMB …, 2020 - Wiley Online Library
Staphylococcus aureus is known as a common pathogen that colonizes 30% of healthy
humans. Additionally, this bacterium can cause a number of serious infections, that is …

Herbal active ingredients: potential for the prevention and treatment of acute lung injury

WY Yu, CX Gao, HH Zhang, YG Wu… - BioMed Research …, 2021 - Wiley Online Library
Acute lung injury (ALI) is a life‐threatening clinical syndrome with high morbidity and
mortality. The main pathological features of ALI are increased alveolar‐capillary membrane …

[HTML][HTML] Mesenchymal stem cells attenuate inflammatory processes in the heart and lung via inhibition of TNF signaling

A Martire, FB Bedada, S Uchida, J Pöling… - Basic research in …, 2016 - Springer
Mesenchymal stem cells (MSC) have been used to treat different clinical conditions although
the mechanisms by which pathogenetic processes are affected are still poorly understood …

Significant anti-inflammatory aziridine-containing indole alkaloids from the Chinese medicinal plant Alstonia scholaris

BY Hu, YL Zhao, ZS Zhou, YY Zhu… - Chemical …, 2023 - pubs.rsc.org
Two unique windmill-like aziridine-containing indole alkaloids, possessing an
unprecedented 6/5/5/6/6/5/3 rigid ring system and an unusual azabicyclo [3.1. 0] hexane …

[HTML][HTML] Small extracellular vesicles derived from Nrf2-overexpressing human amniotic mesenchymal stem cells protect against lipopolysaccharide-induced acute …

L Xu, Y Zhu, C Li, Q Wang, L Ma, J Wang, S Zhang - Biology Direct, 2022 - Springer
Background Acute lung injury (ALI) is a major cause of respiratory failure in critically ill
patients that results in significant morbidity and mortality. Recent studies indicate that cell …

Recent developments of small molecules with anti-inflammatory activities for the treatment of acute lung injury

T Chen, G Zhu, X Meng, X Zhang - European Journal of Medicinal …, 2020 - Elsevier
Abstract Acute Lung Injury (ALI) can be caused by various diseases or conditions such as
sepsis, pneumonia, trauma, shock, and inhalation of toxic gases. Many efforts have been …