Many lines of evidence suggest that mitochondria have a central role in aging-related
neurodegenerative diseases, such as Alzheimer's disease (AD). Mitochondrial dysfunction …

Hyperpolarization chemistry based on reversible exchange of parahydrogen, also known as
Signal Amplification By Reversible Exchange (SABRE), is a particularly simple approach to …

The brain is a highly energetic organ. Although the brain can consume metabolic substrates,
such as lactate, glycogen, and ketone bodies, the energy metabolism in a healthy adult …

Background There is increasing evidence that children or young adults having acquired liver
disease in childhood display neurocognitive impairment which may become more apparent …

Simple Summary Magnetic resonance spectroscopic imaging is an imaging method that can
map the distribution of multiple biochemicals in the human brain in one scan. Using stronger …

Simple Summary This study compared two brain imaging methods, 7T magnetic resonance
spectroscopic imaging (MRSI), which can image metabolic processes, and 3T magnetic …

Parkinson's disease (PD) is characterized by the progressive and asymmetrical
degeneration of the nigrostriatal dopamine neurons and the unilateral presentation of the …

Purpose We present a novel silent echo‐planar spectroscopic imaging (EPSI) readout,
which uses an ultrasonic gradient insert to accelerate MRSI while producing a high spectral …

Achieving high‐resolution and high signal‐to‐noise ratio (SNR) in vivo metabolic imaging
via fast magnetic resonance spectroscopic imaging (MRSI) has been a longstanding …

Background Currently, two major magnetic resonance (MR) vendors provide commercial 7‑T
scanners that are approved by the Food and Drug Administration (FDA) for clinical …