The islets of Langerhans are highly organized structures that have species-specific, three-
dimensional tissue architecture. Islet architecture is critical for proper hormone secretion in …

Nickel (Ni) is a widely utilized heavy metal that can cause environmental pollution and
health hazards. Its safety has attracted the attention of both the environmental ecology and …

Vascular endothelial cells (vECs) in the brain exhibit structural and functional heterogeneity.
Fenestrated, permeable brain vasculature mediates neuroendocrine function, body-fluid …

The zebrafish is a valuable vertebrate model to study cardiovascular formation and function
due to the facile visualization and rapid development of the circulatory system in its …

Single-use plastic production is higher now than ever before. Much of this plastic is released
into aquatic environments, where it is eventually weathered into smaller nanoscale plastics …

The importance of pancreatic endocrine cell activity modulation by autonomic innervation
has been debated. To investigate this question, we established an in vivo imaging model …

Fenestrated and blood-brain barrier (BBB)-forming endothelial cells constitute major brain
capillaries, and this vascular heterogeneity is crucial for region-specific neural function and …

During embryogenesis dynamic changes in tissue architecture transform primitive anlages
to functional organs. Here we document in real time how pancreatic lumens are derived and …

Fenestrated and blood-brain barrier (BBB)-forming endothelial cells constitute major brain
capillaries, and this vascular heterogeneity is crucial for region-specific neural function and …

The pancreatic β-cells sustain systemic glucose homeostasis by producing and secreting
insulin according to the blood glucose levels. Defects in β-cell function are associated with …