Transendothelial migration (TEM) of Th1 and Th17 cells across the blood–brain barrier
(BBB) has a critical role in the development of experimental autoimmune encephalomyelitis …

Glioblastomas are high-grade brain tumours with a poor prognosis and, currently, few
available therapeutic options. This lack of effective treatments has been linked to diverse …

Glioblastoma, also referred to as glioblastoma multiforme (GBM), is grade IV astrocytoma
characterized by being fast‑growing and the most aggressive brain tumor. In adults, it is the …

Cancer is one of the leading non-communicable diseases with highest mortality rates
worldwide. About half of all cancer patients receive radiation treatment in the course of their …

Insights into the molecular pathogenesis of glioblastoma have not yet resulted in relevant
clinical improvement. With standard therapy, which consists of surgical resection with …

Apoptosis and autophagic cell deaths are programmed cell deaths and they play essential
roles in cell survival, growth and development and tumorigenesis. The huge increase of …

Background We conducted this meta-analysis based on eligible trials to investigate the
relationship between phosphatase and tensin homolog (PTEN) genetic mutation and glioma …

Faced with unique immunobiology and marked heterogeneity, treatment strategies for
glioblastoma require therapeutic approaches that diverge from conventional oncological …

This multicenter phase I study aimed to establish the recommended dose (RD) of the
epidermal growth factor receptor (EGFR) inhibitor erlotinib, given as monotherapy or with …

This report presents the historical experience, clinical presentation, treatment, prognosis,
and pathogenesis of gliosarcoma described to date in the English literature. PubMed query …