Thrombosis remains a major problem in our society, manifesting across multiple
demographic groups and with high associated morbidity and mortality. Thrombus …

Staphylococcus aureus (S. aureus) is a common pathogen that can cause many human
diseases, such as skin infection, food poisoning, endocarditis, and sepsis. These diseases …

Background Obesity is an increasing problem in our current society and is expected to keep
rising in incidence. With its multiorigin, complex pathophysiology, it is difficult to treat and …

Staphylococcus aureus infection is associated with increased levels of neutrophil
extracellular traps (NETs) and von Willebrand factor (VWF), and with reduced activity of …

Background Extracellular traps formed by neutrophils (NETs) and eosinophils (EETs) have
been described in coronary thrombi, contributing to thrombus stability. A key mechanism …

Background. The endocardium and cardiac valves undergo severe impact during infective
endocarditis (IE), and the formation of vegetation places IE patients at a heightened risk of …

Background Staphylocoagulase (SCG) is a virulence factor of Staphylococcus aureus, one
of the most lethal pathogens of our times. The complex of SCG with prothrombin (SCG/ProT) …

Neutrophil extracellular traps (NETs) play an essential role in antimicrobial defense.
However, NETs have also been shown to promote and mediate a wide spectrum of …

Rheumatoid arthritis (RA) is a chronic disease characterized by joint inflammation and
severe disability. However, there is a lack of safe and effective drugs for treating RA. In our …

Streptococcus pneumoniae (pneumococcus)-induced cardiac events are one of the life-
threatening infection outcomes of invasive pneumococcal disease. S. pneumoniae has the …