[HTML][HTML] Synaptic neurexin complexes: a molecular code for the logic of neural circuits
TC Südhof - Cell, 2017 - cell.com
Synapses are specialized junctions between neurons in brain that transmit and compute
information, thereby connecting neurons into millions of overlapping and interdigitated …
information, thereby connecting neurons into millions of overlapping and interdigitated …
[HTML][HTML] Genetics of glutamate and its receptors in autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by
deficits in social interaction skills, impaired communication, and repetitive and restricted …
deficits in social interaction skills, impaired communication, and repetitive and restricted …
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder
INTRODUCTION Our understanding of the pathophysiology of psychiatric disorders,
including autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BD) …
including autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BD) …
Autoantibodies to synaptic receptors and neuronal cell surface proteins in autoimmune diseases of the central nervous system
J Dalmau, C Geis, F Graus - Physiological reviews, 2017 - journals.physiology.org
Investigations in the last 10 years have revealed a new category of neurological diseases
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …
Advancing the understanding of autism disease mechanisms through genetics
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological …
fueled remarkable advances in our understanding of its potential neurobiological …
The role of GABAergic signalling in neurodevelopmental disorders
GABAergic inhibition shapes the connectivity, activity and plasticity of the brain. A series of
exciting new discoveries provides compelling evidence that disruptions in a number of key …
exciting new discoveries provides compelling evidence that disruptions in a number of key …
[HTML][HTML] Synaptopathology involved in autism spectrum disorder
Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …
disorders characterized by impaired social communication, social interaction and repetitive …
Common mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disorders
R Gao, P Penzes - Current molecular medicine, 2015 - ingentaconnect.com
Autism Spectrum Disorders (ASD) and Schizophrenia (SCZ) are cognitive disorders with
complex genetic architectures but overlapping behavioral phenotypes, which suggests …
complex genetic architectures but overlapping behavioral phenotypes, which suggests …
Rate of de novo mutations and the importance of father's age to disease risk
Mutations generate sequence diversity and provide a substrate for selection. The rate of de
novo mutations is therefore of major importance to evolution. Here we conduct a study of …
novo mutations is therefore of major importance to evolution. Here we conduct a study of …
Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities
The discovery of the genetic causes of syndromic autism spectrum disorders and intellectual
disabilities has greatly informed our understanding of the molecular pathways critical for …
disabilities has greatly informed our understanding of the molecular pathways critical for …