[HTML][HTML] Phagocytosis in the brain: homeostasis and disease

DA Galloway, AEM Phillips, DRJ Owen… - Frontiers in …, 2019 - frontiersin.org
Microglia are resident macrophages of the central nervous system and significantly
contribute to overall brain function by participating in phagocytosis during development …

[HTML][HTML] Astrocytic phagocytosis contributes to demyelination after focal cortical ischemia in mice

T Wan, W Zhu, Y Zhao, X Zhang, R Ye, M Zuo… - Nature …, 2022 - nature.com
Ischemic stroke can cause secondary myelin damage in the white matter distal to the
primary injury site. The contribution of astrocytes during secondary demyelination and the …

Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke

XY Xiong, L Liu, QW Yang - Progress in neurobiology, 2016 - Elsevier
Microglia/macrophages are the major immune cells involved in the defence against brain
damage. Their morphology and functional changes are correlated with the release of danger …

[HTML][HTML] Crosstalk between the oxidative stress and glia cells after stroke: from mechanism to therapies

G Zhu, X Wang, L Chen, C Lenahan, Z Fu… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

[HTML][HTML] The indispensable roles of microglia and astrocytes during brain development

K Reemst, SC Noctor, PJ Lucassen… - Frontiers in human …, 2016 - frontiersin.org
Glia are essential for brain functioning during development and in the adult brain. Here, we
discuss the various roles of both microglia and astrocytes, and their interactions during brain …

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

H Konishi, T Okamoto, Y Hara, O Komine… - The EMBO …, 2020 - embopress.org
Microglia are the principal phagocytes that clear cell debris in the central nervous system
(CNS). This raises the question, which cells remove cell debris when microglial phagocytic …

Phagocytic microglia and macrophages in brain injury and repair

F Yu, Y Wang, AR Stetler, RK Leak… - CNS neuroscience & …, 2022 - Wiley Online Library
Aims Phagocytosis is the cellular digestion of extracellular particles, such as pathogens and
dying cells, and is a key element in the evolution of central nervous system (CNS) disorders …

[HTML][HTML] The involvement and therapy target of immune cells after ischemic stroke

Z Jian, R Liu, X Zhu, D Smerin, Y Zhong, L Gu… - Frontiers in …, 2019 - frontiersin.org
After ischemic stroke, the integrity of the blood-brain barrier is compromised. Peripheral
immune cells, including neutrophils, T cells, B cells, dendritic cells, and macrophages …

[HTML][HTML] Inflammation after ischemic stroke: the role of leukocytes and glial cells

JY Kim, J Park, JY Chang, SH Kim… - Experimental …, 2016 - ncbi.nlm.nih.gov
The immune response after stroke is known to play a major role in ischemic brain
pathobiology. The inflammatory signals released by immune mediators activated by brain …

[HTML][HTML] Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury

AD Greenhalgh, JG Zarruk, LM Healy… - PLoS …, 2018 - journals.plos.org
Infiltrating monocyte-derived macrophages (MDMs) and resident microglia dominate central
nervous system (CNS) injury sites. Differential roles for these cell populations after injury are …