Statins are competitive inhibitors of hydroxymethylglutaryl-CoA (HMG-CoA) reductase and
have been used to treat elevated low-density lipoprotein cholesterol (LDL-C) for almost four …

Diabetes mellitus is a complex disease. We are increasingly gaining a better understanding
of its mechanisms at the molecular level. From these new insights, better therapeutic …

Abstract Coenzyme Q 10 (CoQ 10) is an essential component of the mitochondrial electron
transport chain. It is also an antioxidant in cellular membranes and lipoproteins. All cells …

Background. Although vaccine rollout for COVID‐19 has been effective in some countries,
there is still an urgent need to reduce disease transmission and severity. We recently carried …

Abstract The 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, or
statins, are administered as first line therapy for hypercholesterolemia, both in primary and …

Mesenchymal stem cell-derived exosomes have been under investigation as potential
treatments for a diverse range of diseases, and many animal and clinical trials have …

Atherosclerosis is a major cause of human cardiovascular disease, which is the leading
cause of mortality around the world. Various physiological and pathological processes are …

Atherosclerosis and its clinical manifestations, coronary and cerebral artery diseases, are
the most common cause of death worldwide. The main pathophysiological mechanism for …

Malnutrition, which commonly occurs in perioperative patients with cancer, leads to
decreased muscle mass, hypoalbuminemia, and edema, thereby increasing the patient's …

Mitochondrial fission is a crucial process in maintaining metabolic homeostasis in normal
physiology and under conditions of stress. Its dysregulation has been associated with …