Beyond the 5-HT2A receptor: classic and nonclassic targets in psychedelic drug action

LP Cameron, J Benetatos, V Lewis… - Journal of …, 2023 - Soc Neuroscience
Serotonergic psychedelics, such as psilocybin and LSD, have garnered significant attention
in recent years for their potential therapeutic effects and unique mechanisms of action …

Psychedelic commercialization: A wide-spanning overview of the emerging psychedelic industry

JS Aday, BS Barnett, D Grossman… - Psychedelic …, 2023 - liebertpub.com
Background: In the wake of positive clinical trial outcomes of psychedelic-assisted
psychotherapy for the treatment of various psychiatric disorders, there has been an influx of …

The zebrafish for preclinical psilocybin research

O Syed, B Tsang, R Gerlai - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
In this review, we discuss the possible utility of zebrafish in research on psilocybin, a
psychedelic drug whose recreational use as well as possible clinical application are gaining …

UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice

DR Rijsketic, AB Casey, DAN Barbosa… - …, 2023 - nature.com
The effects of context on the subjective experience of serotonergic psychedelics have not
been fully examined in human neuroimaging studies, partly due to limitations of the imaging …

[HTML][HTML] Psilocybin restrains activity-based anorexia in female rats by enhancing cognitive flexibility: contributions from 5-HT1A and 5-HT2A receptor mechanisms

K Conn, LK Milton, K Huang, H Munguba… - Molecular …, 2024 - nature.com
Psilocybin has shown promise for alleviating symptoms of depression and is currently in
clinical trials for the treatment of anorexia nervosa (AN), a condition that is characterised by …

[HTML][HTML] A first characterization of the microbiota-resilience link in swine

E Mancin, C Maltecca, YJ Huang, R Mantovani… - Microbiome, 2024 - Springer
Background The gut microbiome plays a crucial role in understanding complex biological
mechanisms, including host resilience to stressors. Investigating the microbiota-resilience …

Psilocybin-assisted psychotherapy as a potential treatment for eating disorders: a narrative review of preliminary evidence

E Koning, E Brietzke - Trends in Psychiatry and …, 2023 - trends.periodikos.com.br
Eating disorders (ED) are a group of potentially severe mental disorders characterized by
abnormal energy balance, cognitive dysfunction and emotional distress. Cognitive …

Utility of preclinical models in the study of psilocybin–A comprehensive review

M Pedicini, ZA Cordner - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Interest in the therapeutic potential of psilocybin across a broad range of neuropsychiatric
disorders is rapidly expanding. Despite promising clinical data and tremendous public …

Psilocybin prevents activity-based anorexia in female rats by enhancing cognitive flexibility: contributions from 5-HT1A and 5-HT2A receptor mechanisms

K Conn, LK Milton, K Huang, H Munguba, J Ruuska… - bioRxiv, 2023 - biorxiv.org
Psilocybin has shown promise for alleviating symptoms of depression and is currently in
clinical trials for the treatment of anorexia nervosa (AN), a condition that is characterised by …

Do psychedelics have therapeutic potential for obesity?

N Fadahunsi, GM Knudsen… - Nature Reviews …, 2023 - nature.com
Classic psychedelics are being revisited as novel drug candidates. Researchers are
investigating the efficacy of psychedelics for disorders such as depression and addiction …