[HTML][HTML] Introducing neurofilament light chain measure in psychiatry: current evidence, opportunities, and pitfalls

F Bavato, C Barro, LK Schnider, J Simrén… - Molecular …, 2024 - nature.com
The recent introduction of new-generation immunoassay methods allows the reliable
quantification of structural brain markers in peripheral matrices. Neurofilament light chain …

[HTML][HTML] Lowered quality of life in long COVID is predicted by affective symptoms, chronic fatigue syndrome, inflammation and neuroimmunotoxic pathways

M Maes, HT Al-Rubaye, AF Almulla… - International journal of …, 2022 - mdpi.com
The physio-affective phenome of Long COVID-19 is predicted by (a) immune-inflammatory
biomarkers of the acute infectious phase, including peak body temperature (PBT) and …

[HTML][HTML] Increased insulin resistance due to Long COVID is associated with depressive symptoms and partly predicted by the inflammatory response during acute …

HK Al-Hakeim, HT Al-Rubaye, AS Jubran… - Brazilian Journal of …, 2023 - SciELO Brasil
Objective: Some months after the remission of acute COVID-19, some individuals show
depressive symptoms, which are predicted by increased peak body temperature (PBT) and …

[HTML][HTML] T helper-1 activation via interleukin-16 is a key phenomenon in the acute phase of severe, first-episode major depressive disorder and suicidal behaviors

AF Almulla, AAA Algon, C Tunvirachaisakul… - Journal of Advanced …, 2023 - Elsevier
Background Immune-inflammatory pathways in major depressive disorder are confined to
the major dysmood disorder (MDMD) phenotype (Maes et al., 2022). No studies have …

Understanding ayahuasca effects in major depressive disorder treatment through invitro metabolomics and bioinformatics

FS Zandonadi, AAR Silva, AAS Melo… - Analytical and …, 2023 - Springer
Emerging insights from metabolomic-based studies of major depression disorder (MDD) are
mainly related to biochemical processes such as energy or oxidative stress, in addition to …

[HTML][HTML] Lower nerve growth factor levels in major depression and suicidal behaviors: effects of adverse childhood experiences and recurrence of illness

M Maes, M Rachayon, K Jirakran, P Sodsai… - Brain Sciences, 2023 - mdpi.com
Major depressive disorder (MDD) and its severe subtype, major dysmood disorder (MDMD),
are distinguished by activation of inflammatory and growth factor subnetworks, which are …

The molecular fingerprint of Neuroinflammation in COVID-19: A comprehensive discussion on molecular mechanisms of Neuroinflammation due to SARS-COV2 …

ZD Zayeri, M Torabizadeh, M Kargar… - Behavioural Brain …, 2024 - Elsevier
Background and objective Severe acute respiratory syndrome coronavirus 2 attacks the
neural system directly and indirectly via various systems, such as the nasal cavity, olfactory …

Brain-targeted autoimmunity is strongly associated with Long COVID and its chronic fatigue syndrome as well as its affective symptoms.

AF Almulla, M Maes, B Zhou, H Al-Hakeim, A Vojdani - medRxiv, 2023 - medrxiv.org
Background: Autoimmune responses contribute to the pathophysiology of Long COVID,
affective symptoms and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) …

T cell activation via the CD40 ligand and transferrin receptor and deficits in T regulatory cells are associated with major depressive disorder and severity of depression

M Rachayon, K Jirakran, P Sodsai, A Sughondhabirom… - medRxiv, 2023 - medrxiv.org
Major depressive disorder (MDD) is associated with T cell activation (Maes et al. 1990-
1993), but no studies have examined the combined effects of T cell activation and deficits in …

Effects of recurrence of illness and adverse childhood experiences on effector, cytotoxic, and regulatory T cells, and cannabinoid receptor-bearing B cells in major …

M Maes, M Rachayon, K Jirakran, A Sughondhabirom… - medRxiv, 2023 - medrxiv.org
Background Major depressive disorder (MDD) is characterized by increased T helper (Th) 1
polarization, T cell activation (eg, CD71+ and CD40L+), and cannabinoid receptor type 2 …