Aquaporins: water channel proteins of the cell membrane

K Takata, T Matsuzaki, Y Tajika - Progress in histochemistry and …, 2004 - Elsevier
Aquaporins (AQP) are integral membrane proteins that serve as channels in the transfer of
water, and in some cases, small solutes across the membrane. They are conserved in …

Structure and functions of aquaporin-4-based orthogonal arrays of particles

H Wolburg, K Wolburg-Buchholz… - International review of …, 2011 - Elsevier
Orthogonal arrays or assemblies of intramembranous particles (OAPs) are structures in the
membrane of diverse cells which were initially discovered by means of the freeze-fracturing …

Signaling mechanisms and pharmacological modulators governing diverse aquaporin functions in human health and disease

K Wagner, L Unger, MM Salman, P Kitchen… - International Journal of …, 2022 - mdpi.com
The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

Mechanisms inducing low bone density in Duchenne muscular dystrophy in mice and humans

A Rufo, A Del Fattore, M Capulli… - Journal of Bone and …, 2011 - academic.oup.com
Patients affected by Duchenne muscular dystrophy (DMD) and dystrophic MDX mice were
investigated in this study for their bone phenotype and systemic regulators of bone turnover …

[HTML][HTML] Aquaporins and glycerol metabolism

T Hibuse, N Maeda, A Nagasawa… - Biochimica et Biophysica …, 2006 - Elsevier
The discovery of aquaporin (AQP) has made a great impact on life sciences. AQPs are a
family of homologous water channels widely distributed in plants, unicellular organisms …

Mutation-independent proteomic signatures of pathological progression in murine models of Duchenne muscular dystrophy

TLE van Westering, HJ Johansson, B Hanson… - Molecular & Cellular …, 2020 - ASBMB
The absence of the dystrophin protein in Duchenne muscular dystrophy (DMD) results in
myofiber fragility and a plethora of downstream secondary pathologies. Although a variety of …

Autoimmune aquaporin-4 myopathy in neuromyelitis optica spectrum

Y Guo, VA Lennon, BFG Popescu, CK Grouse… - JAMA …, 2014 - jamanetwork.com
Importance Documentation of muscle pathology compatible with targeting of sarcolemmal
aquaporin-4 (AQP4) by complement-activating IgG implies involvement of organs beyond …

Novel variants in human Aquaporin-4 reduce cellular water permeability

MD Sorani, Z Zador, E Hurowitz, D Yan… - Human molecular …, 2008 - academic.oup.com
Cerebral edema contributes significantly to morbidity and mortality after brain injury and
stroke. Aquaporin-4 (AQP4), a water channel expressed in astrocytes, plays a key role in …

Super-resolution imaging of aquaporin-4 orthogonal arrays of particles in cell membranes

A Rossi, TJ Moritz, J Ratelade… - Journal of cell …, 2012 - journals.biologists.com
Summary Aquaporin-4 (AQP4) is a water channel expressed in astrocytes, skeletal muscle
and epithelial cells that forms supramolecular aggregates in plasma membranes called …

Aquaporins in development–a review

H Liu, EM Wintour - Reproductive Biology and Endocrinology, 2005 - Springer
Water homeostasis during fetal development is of crucial physiologic importance. It depends
upon maternal fetal fluid exchange at the placenta and fetal membranes, and some …