[HTML][HTML] Aquaporin channels in the heart—physiology and pathophysiology

AO Verkerk, EM Lodder, R Wilders - International journal of molecular …, 2019 - mdpi.com
Mammalian aquaporins (AQPs) are transmembrane channels expressed in a large variety of
cells and tissues throughout the body. They are known as water channels, but they also …

Autoimmune aquaporin-4 myopathy in neuromyelitis optica spectrum

Y Guo, VA Lennon, BFG Popescu, CK Grouse… - JAMA …, 2014 - jamanetwork.com
Importance Documentation of muscle pathology compatible with targeting of sarcolemmal
aquaporin-4 (AQP4) by complement-activating IgG implies involvement of organs beyond …

Implications of aquaglyceroporins 7 and 9 in glycerol metabolism and metabolic syndrome

N Maeda - Molecular aspects of medicine, 2012 - Elsevier
The discovery of water channel protein (aquaporin [AQP]) has made a great impact on life
sciences. So far, 13 AQPs have been identified in human. AQP3, 7, 9, and 10 are …

[HTML][HTML] Mutation-based therapeutic strategies for Duchenne muscular dystrophy: from genetic diagnosis to therapy

A Nakamura - Journal of personalized medicine, 2019 - mdpi.com
Duchenne and Becker muscular dystrophy (DMD/BMD) are X-linked muscle disorders
caused by mutations of the DMD gene, which encodes the subsarcolemmal protein …

Role of membrane complement regulators in neuromyelitis optica

S Saadoun, MC Papadopoulos - Multiple Sclerosis Journal, 2015 - journals.sagepub.com
Background: It is unclear why AQP4-IgG primarily causes central nervous system lesions by
activating complement, but generally spares peripheral AQP4-expressing organs …

Role of aquaporin-7 and aquaporin-9 in glycerol metabolism; involvement in obesity

N Maeda, T Hibuse, T Funahashi - Aquaporins, 2009 - Springer
The discovery of aquaporin (AQP) has had a great impact on life sciences. So far, 13 AQPs
have been identified in human. AQP3, 7, 9, and 10 are subcategorized as …

Cardiac aquaporins

A Rutkovskiy, G Valen, J Vaage - Basic research in cardiology, 2013 - Springer
Aquaporins are a group of proteins with high-selective permeability for water. A subgroup
called aquaglyceroporins is also permeable to glycerol, urea and a few other solutes …

Aquaporins and diseases pathogenesis: From trivial to undeniable involvements, a disease‐based point of view

M Ala, R Mohammad Jafari… - Journal of Cellular …, 2021 - Wiley Online Library
Aquaporins (AQPs), as transmembrane proteins, were primarily identified as water channels
with the ability of regulating the transmission of water, glycerol, urea, and other small‐sized …

Non-coding RNAs and Aquaporin 4: Their Role in the Pathogenesis of Neurological Disorders

Z Yaghoobi, SS Seyed Bagher Nazeri, A Asadi… - Neurochemical …, 2024 - Springer
Neurological disorders are a major group of non-communicable diseases affecting quality of
life. Non-Coding RNAs (ncRNAs) have an important role in the etiology of neurological …

[HTML][HTML] AQP4-dependent water transport plays a functional role in exercise-induced skeletal muscle adaptations

D Basco, B Blaauw, F Pisani, A Sparaneo, GP Nicchia… - PLoS …, 2013 - journals.plos.org
In this study we assess the functional role of Aquaporin-4 (AQP4) in the skeletal muscle by
analyzing whether physical activity modulates AQP4 expression and whether the absence of …