Proteomic alteration in the progression of multiple myeloma: A comprehensive review

NH Ismail, A Mussa, MJ Al-Khreisat, S Mohamed Yusoff… - Diagnostics, 2023 - mdpi.com
Multiple myeloma (MM) is an incurable hematologic malignancy. Most MM patients are
diagnosed at a late stage because the early symptoms of the disease can be uncertain and …

Immunoregulation and clinical significance of neutrophils/NETs-ANGPT2 in tumor microenvironment of gastric cancer

S Yang, X Zou, J Li, H Yang, A Zhang, Y Zhu… - Frontiers in …, 2022 - frontiersin.org
Although significant progress has been made in the study of gastric cancer (GC), clinicians
lack reliable protein markers for accurate diagnosis and tumor stratification. Neutrophil …

The biological function of Serpinb9 and Serpinb9-based therapy

H Huang, Y Mu, S Li - Frontiers in Immunology, 2024 - frontiersin.org
Recent breakthroughs in discovering novel immune signaling pathways have revolutionized
different disease treatments. SERPINB9 (Sb9), also known as Proteinase Inhibitor 9 (PI-9), is …

Changes on proteomic and metabolomic profiling of cryopreserved sperm effected by melatonin

C Li, C Ren, Y Chen, M Wang, J Tang, Y Zhang… - Journal of …, 2023 - Elsevier
Cryopreservation may reduce sperm fertility due to cryodamage including physical-chemical
and oxidative stress damages. As a powerful antioxidant, melatonin has been reported to …

Proteomic analysis of donkey sperm reveals changes in acrosome enzymes and redox regulation during cryopreservation

H Liu, J Yu, M Li, S Kang, X Zhao, G Yin, B Liu, C Ji… - Journal of …, 2022 - Elsevier
Sperm cryoinjuries caused by cryopreservation restrict the application of donkey frozen
semen in artificial insemination (AI). Identification of differentially represented proteins in …

Integrating plasma proteomes with genome-wide association data for causal protein identification in multiple myeloma

Q Wang, Q Shi, Z Wang, J Lu, J Hou - BMC medicine, 2023 - Springer
Background Multiple myeloma (MM) is a severely debilitating and fatal B-cell neoplastic
disease. The discovery of disease-associated proteins with causal genetic evidence offers a …

Combined metabolomic and proteomic analysis of sepsis related acute liver injury and its pathogenesis research

J Zhang, X Wang, Y Peng, J Wei, Y Luo, F Luan… - International …, 2024 - Elsevier
Background Sepsis-induced acute liver injury is common in patients in intensive care units.
However, the exact mechanism of this condition remains unclear. The purpose of this study …

Serum proteomic profiling reveals MTA2 and AGO2 as potential prognostic biomarkers associated with disease activity and adverse outcomes in multiple myeloma

D Apipongrat, S Roytrakul, K Prayongratana… - Plos one, 2022 - journals.plos.org
Multiple myeloma (MM) is an incurable plasma cell malignancy accounting for
approximately 10% of hematological malignancies. Identification of reliable biomarkers for …

TMT proteomics analysis of cerebrospinal fluid from patients with cerebral venous sinus thrombosis

Y Liu, R Ding, M Li, W Ou, X Zhang, W Yang… - Journal of …, 2023 - Elsevier
CVST is a type of venous stroke that mainly affects young adults with no reliable diagnostic
markers and effective treatment strategies for secondary pathologies. However, the …

[HTML][HTML] The application of high-throughput proteomics in cytopathology

IP Nikas, HS Ryu - Journal of Pathology and Translational …, 2022 - ncbi.nlm.nih.gov
High-throughput genomics and transcriptomics are often applied in routine pathology
practice to facilitate cancer diagnosis, assess prognosis, and predict response to therapy …