As naturally occurring bioactive products, several lines of evidence have shown the potential
of polyphenols in the medical intervention of various diseases, including tumors …

The excessive reactive oxygen species (ROS) is a hallmark associated with the initiation
and progression of inflammatory bowel disease (IBD), which execrably form a vicious cycle …

The increased incidence of inflammatory bowel disease (IBD) has seriously affected the life
quality of patients. IBD develops due to excessive intestinal epithelial cell (IEC) apoptosis …

Cartilage-targeting delivery of therapeutic agents is still an effective strategy for osteoarthritis
(OA) therapy. Recently, scavenging for reactive oxygen species (ROS) and activating …

Macrophages play a key role in defending against foreign pathogens, healing wounds, and
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …

Inflammatory bowel disease (IBD) manifests as intestinal barrier destruction, mucosal
immunity dysregulation, and disrupted gut microbiome homeostasis. Conventional anti …

The gastrointestinal tract (GIT) affects not only local diseases in the GIT but also various
systemic diseases. Factors that can affect the health and disease of both GIT and the human …

Activated fibroblast-like synovial (FLS) cells are regarded as an important target for
rheumatoid arthritis (RA) treatment via starvation therapy mediated by glucose oxidase …

Although magnolol (Mag), an anti-inflammatory natural compound, has been demonstrated
to play protective effects on ulcerative colitis (UC), its application as an alternative …

Ulcerative colitis (UC) with its rapidly increasing incidence has become an emerging
challenge for public health. Therapeutic agents are required to be specifically delivered to …