Stimulation-responsive mucoadhesive probiotics for inflammatory bowel disease treatment by scavenging reactive oxygen species and regulating gut microbiota
QX Huang, JL Liang, CH Yang, K Li, MT Niu, JX Fan… - Biomaterials, 2023 - Elsevier
Inflammatory bowel disease (IBD) is characterized by the high level of reactive oxygen
species (ROS) and highly dysfunctional intestinal flora. Here, a stimulation-responsive …
species (ROS) and highly dysfunctional intestinal flora. Here, a stimulation-responsive …
Cyclodextrin-based host-guest complexes loaded with regorafenib for colorectal cancer treatment
The malignancy of colorectal cancer (CRC) is connected with inflammation and tumor-
associated macrophages (TAMs), but effective therapeutics for CRC are limited. To integrate …
associated macrophages (TAMs), but effective therapeutics for CRC are limited. To integrate …
Immunomodulatory biomaterials and their application in therapies for chronic inflammation-related diseases
JR Nakkala, Z Li, W Ahmad, K Wang, C Gao - Acta Biomaterialia, 2021 - Elsevier
The degree of tissue injuries such as the level of scarring or organ dysfunction, and the
immune response against them primarily determine the outcome and speed of healing …
immune response against them primarily determine the outcome and speed of healing …
Advances in the treatment of inflammatory bowel disease: Focus on polysaccharide nanoparticulate drug delivery systems
H Hadji, K Bouchemal - Advanced Drug Delivery Reviews, 2022 - Elsevier
The complex pathogenesis of inflammatory bowel disease (IBD) explains the several
hurdles for finding an efficient approach to cure it. Nowadays, therapeutic protocols aim to …
hurdles for finding an efficient approach to cure it. Nowadays, therapeutic protocols aim to …
[HTML][HTML] Ginsenoside Rg1 ameliorated experimental colitis by regulating the balance of M1/M2 macrophage polarization and the homeostasis of intestinal flora
J Long, XK Liu, ZP Kang, MX Wang, HM Zhao… - European Journal of …, 2022 - Elsevier
Aberrant M1/M2 macrophage polarization and dysbiosis are involved in the pathogenesis of
ulcerative colitis (UC). Ginsenoside Rg1 exhibits optimal immunomodulatory and anti …
ulcerative colitis (UC). Ginsenoside Rg1 exhibits optimal immunomodulatory and anti …
Efficient Therapy of Inflammatory Bowel Disease (IBD) with Highly Specific and Durable Targeted Ta2C Modified with Chondroitin Sulfate (TACS)
X Song, Q Huang, Y Yang, L Ma, W Liu… - Advanced …, 2023 - Wiley Online Library
Non‐invasive localization of lesions and specific targeted therapy are still the main
challenges for inflammatory bowel disease (IBD). Ta, as a medical metal element, has been …
challenges for inflammatory bowel disease (IBD). Ta, as a medical metal element, has been …
Calcium pectinate and hyaluronic acid modified lactoferrin nanoparticles loaded rhein with dual-targeting for ulcerative colitis treatment
R Luo, M Lin, C Fu, J Zhang, Q Chen, C Zhang… - Carbohydrate …, 2021 - Elsevier
Herein, dual-bioresponsive of Rhein (RH) in promoting colonic mucous damage repair and
controlling inflammatory reactions were combined by the dual-targeting (intestinal epithelial …
controlling inflammatory reactions were combined by the dual-targeting (intestinal epithelial …
Synthetic lignin-derived therapeutic nano reagent as intestinal pH-sensitive drug carriers capable of bypassing the gastric acid environment for colitis treatment
C Zhao, J Yang, M Chen, W Chen, X Yang, H Ye… - ACS …, 2022 - ACS Publications
Oral drug delivery is a common route for management of inflammatory bowel disease (IBD)
but suffers from low bioavailability and systemic side effects during passage through the …
but suffers from low bioavailability and systemic side effects during passage through the …
Polydopamine nanoparticle‐mediated dopaminergic immunoregulation in colitis
Despite immunosuppression is critical for reducing immune overactivation, existing
immunosuppressive agents are largely restricted by low inhibition efficiencies and …
immunosuppressive agents are largely restricted by low inhibition efficiencies and …
Orally administered silicon hydrogen nanomaterials as target therapy to treat intestinal diseases
K Wei, F Gong, J Wu, W Tang, F Liao, Z Han, Z Pei… - ACS …, 2023 - ACS Publications
The occurrence and development of inflammatory bowel diseases (IBDs) are inextricably
linked to the excessive production of reactive oxygen species (ROS). Thus, there is an …
linked to the excessive production of reactive oxygen species (ROS). Thus, there is an …