The fast-developing synthetic biology (SB) has provided many genetic tools to reprogram
and engineer cells for improved performance, novel functions, and diverse applications …

Inflammatory bowel disease (IBD), comprising Crohn's disease and ulcerative colitis, is a
refractory disease with many immune abnormalities and pathologies in the gastrointestinal …

Probiotics are generally used as therapeutic intervention in inflammatory bowel disease.
However, the low survival rate in harsh gastrointestinal environment and limited retention in …

Conspectus Therapeutic manipulation of the immune system against cancer has
revolutionized the treatment of several advanced-stage tumors. While many have benefited …

Delivering drugs directly to the inflamed intestinal sites to treat inflammatory bowel disease
(IBD), particularly Crohn's and ulcerative colitis, is highly challenging. Recent advances in …

Ulcerative colitis (UC), affecting millions of patients worldwide, is associated with disorders
of the gut microbiota. Probiotics‐based therapy positively regulating the community structure …

Inflammatory bowel disease (IBD) is a chronic intestinal disease with painful clinical
manifestations and high risks of cancerization. With no curative therapy for IBD at present …

Ulcerative colitis (UC) is a recurrent chronic inflammation of the colon with increasing
incidence and prevalence, which could increase the risk of colorectal cancer. It is urgent to …

Calcium overload is one of the early determinants of the core cellular events that contribute
to the pathogenesis of acute kidney injury (AKI), which include oxidative stress, ATP …

Rationale: Oxidative stress, resulting from excessive reactive oxygen species (ROS), plays
an important role in the initiation and progression of inflammatory bowel disease (IBD) …