Topical gel-based biomaterials for the treatment of diabetic foot ulcers

JR Bardill, MR Laughter, M Stager, KW Liechty… - Acta biomaterialia, 2022 - Elsevier
Diabetic foot ulcers (DFUs) are a devastating ailment for many diabetic patients with
increasing prevalence and morbidity. The complex pathophysiology of DFU wound …

[HTML][HTML] Current knowledge about the new drug firibastat in arterial hypertension

E Hansen, D Grimm, M Wehland - International Journal of Molecular …, 2022 - mdpi.com
Hypertension significantly increases the risk of cardiovascular disease. Currently, effective
standard pharmacological treatment is available in the form of diuretics, ACE inhibitors …

Clinical pharmacokinetics of nebivolol: a systematic review

N Hanif, A Zamir, I Imran, H Saeed… - Drug Metabolism …, 2023 - Taylor & Francis
Nebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile
dysfunction, vascular disease, and diabetes mellitus. This review investigated the data …

Nanosized ethosomal dispersions for enhanced transdermal delivery of nebivolol using intradermal/transfollicular sustained reservoir: in vitro evaluation, confocal laser …

SA Fouad, ST Khatab, MH Teaima… - Pharmaceutical …, 2024 - Taylor & Francis
Nebivolol (NBV), a BCS class II anti-hypertensive drug, suffers from limited solubility and
oral bioavailability. Nanosized ethosomes were adopted as an approach to solubilize and …

Formulation, optimization and in vitro evaluation of polymer-coated liposomes encapsulating nebivolol hydrochloride

M Sessevmez, G Sinani, T Çevikelli - International Journal of …, 2024 - Taylor & Francis
Hypertension, also known as high blood pressure, is a serious medical condition that affects
billions of people worldwide. Nebivolol hydrochloride, a β1–adrenergic blocking agent, is …

[HTML][HTML] New data for nebivolol after in silico PK study: focus on young patients and dosage regimen

L Marques, B Costa, N Vale - Pharmaceutics, 2022 - mdpi.com
Nebivolol (NEB) is a highly selective β1 receptor antagonist with a distinct pharmacological
profile. This drug is approved for the treatment of hypertension in the US, and hypertension …

Linked biaromatic compounds as cardioprotective agents

GV Mokrov - Archiv der Pharmazie, 2022 - Wiley Online Library
Cardiovascular diseases (CVDs) are widespread in the modern world, and their number is
constantly growing. For a long time, CVDs have been the leading cause of morbidity and …

[HTML][HTML] Antidepressant sertraline is a broad-spectrum inhibitor of enteroviruses targeting viral entry through neutralization of endolysosomal acidification

KC Tseng, BY Hsu, P Ling, WW Lu, CW Lin, SH Kung - Viruses, 2022 - mdpi.com
Enterovirus 71 (EV71) is an etiological agent of hand foot and mouth disease and can also
cause neurological complications in young children. However, there are no approved drugs …

The role of nebivolol in the management of hypertensive patients: from pharmacological profile to treatment guidelines

C Ferri - Future Cardiology, 2021 - Taylor & Francis
According to the most recent international guidelines, β-blockers maintain a central role in
the management of hypertension, being recommended at any treatment step when there is a …

Lipid Horizons: Recent Advances and Future Prospects in LBDDS for Oral Administration of Antihypertensive Agents

Preeti, S Sambhakar, R Malik, S Bhatia… - International Journal …, 2024 - Wiley Online Library
The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is
anticipated to bring about comprehensive transformations in the pharmaceutical field …