Rapidly emerging evidence continues to describe an intimate and causal relationship
between sleep and emotional brain function. These findings are mirrored by long-standing …

Major depressive disorder is one of the most common psychiatric illnesses in the United
States, with an estimated lifetime prevalence of up to 17%. 1 Affected individuals are at high …

Background The chronotype, being a morning or an evening type, can influence an
individual's psychological health. Studies have shown a link between depressed mood and …

Objectives To examine (i) the frequency of different sleep complaints (early wake-up, trouble
falling asleep, hypersomnia) and their co-occurrence and (ii) the sociodemographic …

The importance of time is ever prevalent in our world, and disruptions to the normal
light/dark and sleep/wake cycle have now become the norm rather than the exception for a …

Light therapy'is established worldwide as the treatment of choice for seasonal affective
disorder. It is also successfuly used in nonseasonal depression, as well as for many other …

Major depressive disorder is among the most commonly diagnosed disabling mental
diseases. Several non-pharmacological treatments of depression upregulate adenosine …

Aims To systematically review the literature on the efficacy and tolerability of the major
chronotherapeutic treatments of bipolar disorders (BD)—bright light therapy (LT), dark …

Conventional antidepressants require 2–8 weeks for a full clinical response. In contrast, two
rapidly acting antidepressant interventions, low-dose ketamine and sleep deprivation (SD) …

According to the recently proposed vigilance model of affective disorders (vigilance in the
sense of “brain arousal”), manic behaviour is partly interpreted as an autoregulatory attempt …