The management of hepatocellular carcinoma. Current expert opinion and recommendations derived from the 24th ESMO/World Congress on Gastrointestinal Cancer …

M Ducreux, GK Abou-Alfa, T Bekaii-Saab, J Berlin… - ESMO open, 2023 - Elsevier
Highlights•The incidence of HCC will continue to rise.•HCC is curable at an early
stage.•New locoregional treatments such as radioembolisation are showing impressive …

Effectiveness and safety of atezolizumab-bevacizumab in patients with unresectable hepatocellular carcinoma: a systematic review and meta-analysis

AV Kulkarni, H Tevethia, K Kumar, M Premkumar… - …, 2023 - thelancet.com
Background Atezolizumab-bevacizumab (atezo-bev) is recommended as first-line therapy
for patients with unresectable hepatocellular carcinoma (uHCC). However, its effectiveness …

Evaluation of lactate dehydrogenase and alkaline phosphatase as predictive biomarkers in the prognosis of hepatocellular carcinoma and development of a new …

K Su, W Huang, X Li, K Xu, T Gu, Y Liu… - Journal of …, 2023 - Taylor & Francis
Background Tumor proliferation is frequently accompanied by aberrant enzyme production.
We aim to investigate the potential predictive value of both plasma alkaline phosphatase …

The MAPS-CRAFITY score: a novel efficacy predictive tool for unresectable hepatocellular carcinoma treated with targeted therapy plus immunotherapy

J Ouyang, Y Yang, Y Zhou, F Ye, Z Wang, Q Li… - Hepatology …, 2023 - Springer
Abstract Background Body composition parameters (BCPs) are associated with mortality in
patients with hepatocellular carcinoma (HCC). Our purpose was to develop a practical …

[HTML][HTML] Characteristics and outcomes of immunotherapy-related liver injury in patients with hepatocellular carcinoma versus other advanced solid tumours

C Celsa, G Cabibbo, CAM Fulgenzi, B Scheiner… - Journal of …, 2024 - Elsevier
Background & Aims Immune-related liver injury (irLI) is commonly observed in patients with
cancer treated with immune checkpoint inhibitors (ICIs). We aimed to compare the …

Thyroid dysfunction after atezolizumab and bevacizumab is associated with favorable outcomes in hepatocellular carcinoma

Y Song, H Yang, B Kang, J Cheon, I Kim, H Kim, W Lee… - Liver Cancer, 2023 - karger.com
Abstract Introduction: Atezolizumab and bevacizumab (Ate/Bev) combination has become
the new first-line systemic therapy for unresectable hepatocellular carcinoma (HCC) …

Efficacy and safety of atezolizumab plus bevacizumab treatment for advanced hepatocellular carcinoma in the real world: a single-arm meta-analysis

X Gao, R Zhao, H Ma, S Zuo - BMC cancer, 2023 - Springer
Background Atezolizumab plus bevacizumab was approved in 2020 as a first-line treatment
for advanced hepatocellular carcinoma (HCC). The purpose of this study was to assess the …

Objective response and progression-free survival contribute to prolong overall survival in atezolizumab plus bevacizumab treatment for unresectable hepatocellular …

K Tajiri, K Tsukada, Y Tokimitsu, Y Motofuji, K Kawai… - Oncology, 2024 - karger.com
Objective Response and Progression-Free Survival Contribute to Prolong Overall Survival in
Atezolizumab plus Bevacizumab Treatment for Unresectable Hepatocellular Carcinoma …

The New era of systemic treatment for hepatocellular carcinoma: from the first line to the optimal sequence

M Cerreto, F Cardone, L Cerrito, L Stella… - Current …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) represents the most common primary liver cancer and is
considered a major global health problem as one of the leading causes of cancer-related …

Impact of radiological response and pattern of progression in patients with HCC treated by atezolizumab-bevacizumab

C Campani, A Vallot, H Ghannouchi, M Allaire… - Hepatology, 2024 - journals.lww.com
Conclusions: RECIST 1.1 and mRECIST criteria predict overall survival with more
responders identified by mRECIST and the appearance of new extrahepatic lesion or …