[HTML][HTML] Effect of biological sex on human circulating lipidome: an overview of the literature
R Tabassum, E Widén, S Ripatti - Atherosclerosis, 2023 - Elsevier
Cardiovascular diseases (CVD) are the leading cause of death worldwide for both men and
women, but their prevalence and burden show marked sex differences. The existing …
women, but their prevalence and burden show marked sex differences. The existing …
Lipidome‐and genome‐wide study to understand sex differences in circulatory lipids
R Tabassum, S Ruotsalainen… - Journal of the …, 2022 - Am Heart Assoc
Background Despite well‐recognized differences in the atherosclerotic cardiovascular
disease risk between men and women, sex differences in risk factors and sex‐specific …
disease risk between men and women, sex differences in risk factors and sex‐specific …
Omic-scale high-throughput quantitative LC–MS/MS approach for circulatory lipid phenotyping in clinical research
Lipid analysis at the molecular species level represents a valuable opportunity for clinical
applications due to the essential roles that lipids play in metabolic health. However, a …
applications due to the essential roles that lipids play in metabolic health. However, a …
Circulating metabolome and white matter hyperintensities in women and men
Background: White matter hyperintensities (WMH), identified on T2-weighted magnetic
resonance images of the human brain as areas of enhanced brightness, are a major risk …
resonance images of the human brain as areas of enhanced brightness, are a major risk …
[HTML][HTML] Lipidome characterisation and sex-specific differences in type 1 and type 2 diabetes mellitus
M Barranco-Altirriba, N Alonso, RJM Weber… - Cardiovascular …, 2024 - Springer
Background In this study, we evaluated the lipidome alterations caused by type 1 diabetes
(T1D) and type 2 diabetes (T2D), by determining lipids significantly associated with diabetes …
(T1D) and type 2 diabetes (T2D), by determining lipids significantly associated with diabetes …
[HTML][HTML] Sphingolipids are depleted in alcohol-related liver fibrosis
Background & Aims Alcohol disturbs hepatic lipid synthesis and transport, but the role of
lipid dysfunction in alcohol-related liver disease (ALD) is unclear. In this biopsy-controlled …
lipid dysfunction in alcohol-related liver disease (ALD) is unclear. In this biopsy-controlled …
Plasma Ceramides and Sphingomyelins and Sudden Cardiac Death in the Cardiovascular Health Study
LB Bockus, PN Jensen, AM Fretts… - JAMA Network …, 2023 - jamanetwork.com
Importance Sphingolipids, including ceramides and sphingomyelins, may influence the
pathophysiology and risk of sudden cardiac death (SCD) through multiple biological …
pathophysiology and risk of sudden cardiac death (SCD) through multiple biological …
[HTML][HTML] Sex differences in associations of plasma metabolites with blood pressure and heart rate variability: The HELIUS study
Background and aims Since plasma metabolites can modulate blood pressure (BP) and
vary between men and women, we examined sex differences in plasma metabolite profiles …
vary between men and women, we examined sex differences in plasma metabolite profiles …
Sex-dependent differences in stress-induced depression in Wistar rats are accompanied predominantly by changes in phosphatidylcholines and sphingomyelins
A Leskanicova, M Babincak, F Mochnacky… - Journal of Physiology …, 2021 - zora.uzh.ch
With a high annual and lifetime prevalence, depression is becoming the leading contributor
to the global disease burden. During the COVID-19 crisis, the depression and mood …
to the global disease burden. During the COVID-19 crisis, the depression and mood …
The bone marrow lipidomics of mice reveal sex‐related differences
Z Zhong, Z Hu, W Zhou, X Qin… - Biomedical …, 2024 - Wiley Online Library
Osteoporosis is a common skeletal disorder characterized by an imbalance between bone
resorption and formation, exhibiting a higher prevalence in women compared with men …
resorption and formation, exhibiting a higher prevalence in women compared with men …