Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment

Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …

The role of exosomal noncoding RNAs in cancer

Y Xie, W Dang, S Zhang, W Yue, L Yang, X Zhai… - Molecular cancer, 2019 - Springer
Extracellular vesicles (EVs) membranes enclose nanosized vesicles with a size range of 30–
150 nm and are plentiful in our body in both physiological and pathological conditions …

[HTML][HTML] Exosomes as potential sources of biomarkers in colorectal cancer

Y Xiao, J Zhong, B Zhong, J Huang, L Jiang, Y Jiang… - Cancer letters, 2020 - Elsevier
Colorectal cancer (CRC), a common malignancy, is among the leading causes of cancer-
related deaths worldwide. Developing novel biomarkers is an important public health …

Liquid biopsies, novel approaches and future directions

A Armakolas, M Kotsari, J Koskinas - Cancers, 2023 - mdpi.com
Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …

miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review

MT Di Martino, M Arbitrio, D Caracciolo… - … Therapy-Nucleic Acids, 2022 - cell.com
Among deregulated microRNAs (miRs) in human malignancies, miR-221 has been widely
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …

Advanced nanotechnologies for extracellular vesicle‐based liquid biopsy

L Min, B Wang, H Bao, X Li, L Zhao, J Meng… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are emerging as a new source of biomarkers in liquid biopsy
because of their wide presence in most body fluids and their ability to load cargoes from …

[HTML][HTML] Reducing anastomotic leak in colorectal surgery: The old dogmas and the new challenges

J Meyer, S Naiken, N Christou, E Liot… - World journal of …, 2019 - ncbi.nlm.nih.gov
Anastomotic leak (AL) constitutes a significant issue in colorectal surgery, and its incidence
has remained stable over the last years. The use of intra-abdominal drain or the use of …

The functional roles of exosomal long non-coding RNAs in cancer

M Wang, L Zhou, F Yu, Y Zhang, P Li… - Cellular and Molecular Life …, 2019 - Springer
Exosomes are extracellular membranous vesicles that are secreted by various cell types.
Exosomes have become indispensable facilitators in the exchange of information between …

[HTML][HTML] Diagnostic and prognostic potential of tissue and circulating long non-coding RNAs in colorectal tumors

O Galamb, BK Barták, A Kalmár, ZB Nagy… - World journal of …, 2019 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are members of the non-protein coding RNA family
longer than 200 nucleotides. They participate in the regulation of gene and protein …