Microarray, gene sequencing, and reverse transcriptase–polymerase chain reaction analyses of a cryptic PML-RARA translocation
J Koshy, YW Qian, G Bhagwath, M Willis, TW Kelley… - Cancer Genetics, 2012 - Elsevier
Acute promyelocytic leukemia (APL) is a well-defined subtype of acute myeloid leukemia
(AML) specifically characterized by the t (15; 17)(q22; q12) translocation. The t (15; 17) …
(AML) specifically characterized by the t (15; 17)(q22; q12) translocation. The t (15; 17) …
The genetic characterization of acute promyelocytic leukemia with cryptic t (15; 17) including a new recurrent additional cytogenetic abnormality i (17)(q10)
M Kim, J Lim, Y Kim, K Han, DH Lee, NG Chung, B Cho… - Leukemia, 2008 - nature.com
It is important to detect PML/RARa rearrangement in patient with morphologic acute
promyelocytic leukemia (APL). Rare cases of APL lacking the classic t (15; 17) on routine …
promyelocytic leukemia (APL). Rare cases of APL lacking the classic t (15; 17) on routine …
Interstitial insertion of RARα gene into PML gene in a patient with acute promyelocytic leukemia (APL) lacking the classic t(15;17)
N Goldschmidt, O Yehuda-Gafni, D Abeliovich… - …, 2010 - Taylor & Francis
The diagnosis of APL is based on clinical and morphological tests though the final diagnosis
is at the molecular level. An accurate diagnosis is important as it mandates targeted therapy …
is at the molecular level. An accurate diagnosis is important as it mandates targeted therapy …
Characterization of chromosomal rearrangements in hematological diseases using spectral karyotyping
J Tchinda, TE Neumann, S Volpert… - Diagnostic Molecular …, 2004 - journals.lww.com
Since chromosomal changes are used both as independent prognostic factors and for
therapy design in hematological disorders, it is necessary to elucidate chromosomal …
therapy design in hematological disorders, it is necessary to elucidate chromosomal …
Acute promyelocytic leukemia lacking the classic translocation t (15; 17)
JJ Wakim, CA Tirado - Myeloid leukemia—clinical diagnosis and …, 2012 - books.google.com
Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML)
characterized by the reciprocal translocation t (15; 17)(q22; q12) resulting in the fusion gene …
characterized by the reciprocal translocation t (15; 17)(q22; q12) resulting in the fusion gene …
[PDF][PDF] Distribution of PML-RARA isoforms in Acute promyelocytic leukemia patients from a tertiary hospital in KZN, South Africa using qPCR.
E Safiya - 2017 - core.ac.uk
Leukemia represents a group of hematological malignancies characterized by clonal
expansion of hematopoietic cells with uncontrolled proliferation, decreased apoptosis and …
expansion of hematopoietic cells with uncontrolled proliferation, decreased apoptosis and …
Fluroscence in-situ hybridization negative PML/RARA: A cryptic puzzle
MC Mundada, F Ahmed, GS Devi… - Indian Journal of …, 2015 - journals.lww.com
Acute promyelocytic leukemia (APL) has defined biology and clinical course that is, distinct
from the other forms of acute myelogenous leukemia. It may present with potentially …
from the other forms of acute myelogenous leukemia. It may present with potentially …