Far-red fluorescent probes for canonical and non-canonical nucleic acid structures: current progress and future implications

YV Suseela, N Narayanaswamy, S Pratihar… - Chemical Society …, 2018 - pubs.rsc.org
The structural diversity and functional relevance of nucleic acids (NAs), mainly
deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are indispensable for almost all …

Structurally diverse G-quadruplexes as the noncanonical nucleic acid drug target for live cell imaging and antibacterial study

BX Zheng, J Yu, W Long, KH Chan… - Chemical …, 2023 - pubs.rsc.org
The formation of G-quadruplex structures (G4s) in vitro from guanine (G)-rich nucleic acid
sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …

[HTML][HTML] Recent developments in novel blue/green/red/NIR small fluorescent probes for in cellulo tracking of RNA/DNA G-quadruplexes

A Pandith, RG Siddappa, YJ Seo - Journal of Photochemistry and …, 2019 - Elsevier
The detection and stabilization of G-quadruplexes (G4s) in living systems is of enormous
applicability in the fields of chemical biology and therapeutic materials. Whereas DNA …

Antibacterial activity of indolyl-quinolinium derivatives and study their mode of action

S Cai, W Yuan, Y Li, X Huang, Q Guo, Z Tang… - Bioorganic & medicinal …, 2019 - Elsevier
Filamenting temperature-sensitive mutant Z (FtsZ) is recognized as a promising target for
new antibiotics development because of its high conservatism and pivotal role in the …

Unique development of a new dual application probe for selective detection of antiparallel G-quadruplex sequences

V Babagond, K Katagi, A Pandith, M Akki, A Jaggal - Analyst, 2023 - pubs.rsc.org
G-Quadruplex (G4) structures play vital roles in many biological processes; consequently,
they have been implicated in various human diseases like cancer, Alzheimer's disease etc …

A near-infrared and mitochondria-targeted fluorescence probe for ratiometric monitoring of sulfur dioxide derivatives in living cells

YH Yan, XY He, JY Miao, BX Zhao - Journal of Materials Chemistry B, 2019 - pubs.rsc.org
A promising near-infrared emissive and mitochondria-targeted fluorescence probe (SNB) for
the ratiometric detection of sulfur dioxide derivatives with a novel reaction mechanism was …

Stabilization and fluorescence light-up of G-quadruplex nucleic acids using indolyl-quinolinium based probes

A Biswas, SB Singh, CS Todankar… - Physical Chemistry …, 2022 - pubs.rsc.org
G-Quadruplexes (G4s) are four-stranded motifs formed by G-rich nucleic acid sequences.
These structures harbor significant biological importance as they are involved in telomere …

Quadruplex detection in human cells

D Monchaud - Annual Reports in Medicinal Chemistry, 2020 - Elsevier
The precise detection of both DNA and RNA quadruplexes in human cells remains
challenging. Efforts are being invested to design, synthesize and operate molecular tools to …

Rational design of Red fluorescent and selective G-quadruplex DNA sensing probes: The study of interaction signaling and the molecular structural relationship …

BX Zheng, W Long, YH Zhang, XH Huang… - Sensors and Actuators B …, 2020 - Elsevier
Red fluorescent G-quadruplex DNA selective organic binding probe is relatively
underdeveloped. In the present study, we designed a series of new fluorescent probes that …

Advancing small ligands targeting RNA for better binding affinity and specificity: A study of structural influence through molecular design approach

C Wang, YJ Lu, SY Cai, W Long, YY Zheng… - Sensors and Actuators B …, 2018 - Elsevier
The cell permeable small fluorescent organic molecules possessing RNA-specific binding
property were synthesized for the study of structural influence on two determining factors of …