Evolutionary ecology of Chagas disease; what do we know and what do we need?

A Flores‐Ferrer, O Marcou, E Waleckx… - Evolutionary …, 2018 - Wiley Online Library
The aetiological agent of Chagas disease, Trypanosoma cruzi, is a key human pathogen
afflicting most populations of Latin America. This vectorborne parasite is transmitted by …

Insecticide resistance in triatomines

G Mougabure-Cueto, MI Picollo - … -The Biology of Chagas Disease Vectors, 2021 - Springer
The control of Chagas disease vectors has been based principally on spraying dwellings
with insecticides. This strategy reduced the geographic range and infestation prevalence of …

Chagas disease vector control

RE Gürtler, MC Cecere - Triatominae-The biology of chagas disease …, 2021 - Springer
Most of the human infections with Trypanosoma cruzi are caused by triatomine species
adapted to thrive in domestic habitats and blood-feed on humans. Residual house spraying …

The Pampa del Indio project: District-wide quasi-elimination of Triatoma infestans after a 9-year intervention program in the Argentine Chaco

RE Gürtler, MS Gaspe, NP Macchiaverna… - PLOS Neglected …, 2023 - journals.plos.org
Background The elimination of Triatoma infestans, the main domestic vector of
Trypanosoma cruzi, is lagging behind expectations in the Gran Chaco region. We …

Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period

MS Gaspe, YM Provecho, MP Fernandez… - PLoS neglected …, 2018 - journals.plos.org
Background Rapid reinfestation of insecticide-treated dwellings hamper the sustained
elimination of Triatoma infestans, the main vector of Chagas disease in the Gran Chaco …

Transcriptomic modulation in response to an intoxication with deltamethrin in a population of Triatoma infestans with low resistance to pyrethroids

L Traverso, JM Latorre Estivalis… - PLoS Neglected …, 2022 - journals.plos.org
Background Triatoma infestans is the main vector of Chagas disease in the Southern Cone.
The resistance to pyrethroid insecticides developed by populations of this species impairs …

An oral dose of Fluralaner administered to dogs kills pyrethroid-resistant and susceptible Chagas disease vectors for at least four months

MA Laiño, MV Cardinal, GF Enriquez, A Alvedro… - Veterinary …, 2019 - Elsevier
New vector control tools that can fit into a broader integrated vector management strategy
are notably lacking. We conducted a seven-month randomized trial to assess the efficacy of …

Control of pyrethroid‐resistant populations of Triatoma infestans, the main vector of Trypanosoma cruzi, by treating dogs with fluralaner in the Argentine Chaco

MA Laiño, MV Cardinal, MS Gaspe… - Medical and …, 2022 - Wiley Online Library
We assessed whether fluralaner administered to outbred healthy dogs reduced or
supressed site infestation and abundance of pyrethroid‐resistant populations of Triatoma …

Population structure and migration in Triatoma infestans (Hemiptera: Reduviidae) from the Argentine Chaco: An integration of genetic and morphometric data

RV Piccinali, MS Gaspe, J Nattero, RE Gürtler - Acta Tropica, 2023 - Elsevier
Genetic and morphological structure of vector populations are useful to identify panmictic
groups, reinfestation sources and minimal units for control interventions. Currently, no …

Improved vector control of Triatoma infestans limited by emerging pyrethroid resistance across an urban-to-rural gradient in the Argentine Chaco

MS Gaspe, MV Cardinal, MP Fernández… - Parasites & …, 2021 - Springer
Background The sustainable elimination of Triatoma infestans in the Gran Chaco region
represents an enduring challenge. Following the limited effects of a routine pyrethroid …