In situ self-assembly for cancer therapy and imaging

J Kim, S Lee, Y Kim, M Choi, I Lee, E Kim… - Nature Reviews …, 2023 - nature.com
In situ self-assembly—the in situ formation of complex materials via biochemical reactions of
monomers—has enhanced the efficacy of drug delivery for cancer therapy and imaging. So …

Salivary gland function, development, and regeneration

AM Chibly, MH Aure, VN Patel… - Physiological …, 2022 - journals.physiology.org
Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

[HTML][HTML] Radiation-induced salivary gland dysfunction: mechanisms, therapeutics and future directions

KJ Jasmer, KE Gilman, K Muñoz Forti… - Journal of clinical …, 2020 - mdpi.com
Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …

Head and neck cancer

A Argiris, MV Karamouzis, D Raben, RL Ferris - The Lancet, 2008 - thelancet.com
Most head and neck cancers are squamous cell carcinomas that develop in the upper
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol …

[HTML][HTML] Acoustofluidic salivary exosome isolation: a liquid biopsy compatible approach for human papillomavirus–associated oropharyngeal cancer detection

Z Wang, F Li, J Rufo, C Chen, S Yang, L Li… - The Journal of Molecular …, 2020 - Elsevier
Previous efforts to evaluate the detection of human papilloma viral (HPV) DNA in whole
saliva as a diagnostic measure for HPV-associated oropharyngeal cancer (HPV-OPC) have …

Xerostomia of various etiologies: A review of the literature.

M Tanasiewicz, T Hildebrandt… - Advances in clinical and …, 2016 - europepmc.org
This paper presents the etiopathogenesis, symptomatology, evaluation and treatment of
mouth dryness. Xerostomia affects 1-29% of the population, mostly women. It is observed in …

[HTML][HTML] A review on xerostomia and its various management strategies: the role of advanced polymeric materials in the treatment approaches

A Kapourani, KN Kontogiannopoulos, AE Manioudaki… - Polymers, 2022 - mdpi.com
The medical term xerostomia refers to the subjective sensation of oral dryness. The etiology
seems to be multifactorial with the most frequently reported causes being the use of …

[HTML][HTML] Comprehensive toxicity risk profiling in radiation therapy for head and neck cancer: A new concept for individually optimised treatment

L Van den Bosch, A van der Schaaf… - Radiotherapy and …, 2021 - Elsevier
Background and purpose A comprehensive individual toxicity risk profile is needed to
improve radiation treatment optimisation, minimising toxicity burden, in head and neck …

[HTML][HTML] Cellular senescence contributes to radiation-induced hyposalivation by affecting the stem/progenitor cell niche

X Peng, Y Wu, U Brouwer, T van Vliet, B Wang… - Cell death & …, 2020 - nature.com
Radiotherapy for head and neck cancer is associated with impairment of salivary gland
function and consequent xerostomia, which has a devastating effect on the quality of life of …

[HTML][HTML] Salivary secretory disorders, inducing drugs, and clinical management

J Miranda-Rius, L Brunet-Llobet… - … journal of medical …, 2015 - ncbi.nlm.nih.gov
Background: Salivary secretory disorders can be the result of a wide range of factors. Their
prevalence and negative effects on the patient's quality of life oblige the clinician to confront …