Artificial sweeteners (AS) are synthetic sugar substitutes that are commonly consumed in the
diet. Recent studies have indicated considerable health risks which links the consumption of …

Studies on the anaerobic bacteria Porphyromonas, mainly focused on P. gingivalis, have
revealed new bacterial structures, metabolic pathways, and physiologic functionalities …

Porphyromonas gingivalis is an oral human pathogen associated with the onset and
progression of periodontitis, a chronic immune-inflammatory disease characterized by the …

Probiotics have aroused increasing concern as an intervention strategy for periodontitis
(PD), but their underlying mechanism of action remains poorly characterized. Regarding the …

Objective It aims to explore the effect of dental follicle cells‐derived small extracellular
vesicles (D‐sEVs) with or without lipopolysaccharides (LPS) pretreating on the pathogenicity …

Introduction Porphyromonas gulae have the enzyme PPAD, as P. gingivalis, which is
responsible for citrullination related to the pathophysiology of rheumatoid arthritis and …

Introduction Periodontal disease is a ubiquitous disease in small animal veterinary
medicine. Currently regular professional dental cleaning and daily tooth brushing are …

Porphyromonas gulae is a major periodontal pathogen in dogs, which can be transmitted to
their owners. A major virulence factor of P. gulae consists of a 41-kDa filamentous …

COR388, a small‐molecule lysine‐gingipain inhibitor, is currently being investigated in a
Phase 2/3 clinical trial for Alzheimer's disease (AD) with exploratory endpoints in periodontal …

Chronic periodontitis caused by Porphyromonas gingivalis (P. gingivalis) infection generally
lasts for a lifetime. The long-term existence and development of P. gingivalis infection …