With oxidative injury as well as in some solid tumors and myeloid leukemia cells, heme
oxygenase-1 (HO-1), the anti-oxidant, anti-inflammatory, and anti-apoptotic microsomal …

NAD (P) H: quinone oxidoreductase 1 (NQO1) is an obligate two-electron reductase that is
involved in chemoprotection and can also bioactivate certain antitumor quinones. This …

One of the unique features of β-cells is their relatively low expression of many antioxidant
enzymes. This could render β-cells susceptible to oxidative damage but may also provide a …

Environmental risk factors, including noise, air pollution, chemical agents, ultraviolet
radiation (UVR) and mental stress have a considerable impact on human health. Oxidative …

Iron is required for normal cell growth and proliferation. However, excess iron is potentially
harmful, as it can catalyse the formation of toxic reactive oxygen species (ROS) via Fenton …

Northern blotting has shown that mouse small intestine contains relatively large amounts of
the nuclear factor-E2 p45-related factor (Nrf) 2 transcription factor but relatively little Nrf1 …

When looking for a book on fish toxicology, you might find one that discusses the
biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You …

Proteasomes degrade damaged proteins formed during oxidative stress, thereby promoting
cell survival. Neurodegenerative and other age-related disorders are associated with …

▪ Abstract Mammalian iron homeostasis is maintained through the concerted action of
sensory and regulatory networks that modulate the expression of proteins of iron metabolism …

The molecular mechanisms through which oxidized lipids and their electrophilic
decomposition products mediate redox cell signalling is not well understood and may …