Endothelial to mesenchymal transition in health and disease

Y Xu, JC Kovacic - Annual Review of Physiology, 2023 - annualreviews.org
The endothelium is one of the largest organ systems in the body, and data continue to
emerge regarding the importance of endothelial cell (EC) dysfunction in vascular aging and …

Recent advances and directions in the development of bioresorbable metallic cardiovascular stents: insights from recent human and in vivo studies

AA Oliver, M Sikora-Jasinska, AG Demir, RJ Guillory II - Acta Biomaterialia, 2021 - Elsevier
Over the past two decades, significant advancements have been made regarding the
material formulation, iterative design, and clinical translation of metallic bioresorbable stents …

Pulse wave and vector flow Imaging for atherosclerotic disease progression in hypercholesterolemic swine

P Kemper, GM Karageorgos, D Fodera, N Lee… - Scientific Reports, 2023 - nature.com
Non-invasive monitoring of atherosclerosis remains challenging. Pulse Wave Imaging (PWI)
is a non-invasive technique to measure the local stiffness at diastolic and end-systolic …

[HTML][HTML] Multi-omic analysis in a metabolic syndrome porcine model implicates arachidonic acid metabolism disorder as a risk factor for atherosclerosis

SS Xu, XL Zhang, SS Liu, ST Feng, GM Xiang… - Frontiers in …, 2022 - frontiersin.org
Background The diet-induced gut microbiota dysbiosis has been suggested as a major risk
factor for atherothrombosis, however, the detailed mechanism linking these conditions is yet …

Non-mouse models of atherosclerosis: approaches to exploring the translational potential of new therapies

D Kamato, I Ilyas, S Xu, PJ Little - International Journal of Molecular …, 2022 - mdpi.com
Cardiovascular disease is the largest single cause of disease-related mortality worldwide
and the major underlying pathology is atherosclerosis. Atherosclerosis develops as a …

High-fidelity porcine models of metabolic syndrome: a contemporary synthesis

GL Cluzel, PM Ryan, FM Herisson… - American Journal of …, 2022 - journals.physiology.org
This review aims to describe and compare porcine models of metabolic syndrome. This
syndrome and its associated secondary comorbidities are set to become the greatest …

Identification of Body Size Determination Related Candidate Genes in Domestic Pig Using Genome-Wide Selection Signal Analysis

B Pan, H Long, Y Yuan, H Zhang, Y Peng, D Zhou… - Animals, 2022 - mdpi.com
Simple Summary In this study, the pairwise fixation index (FST) and π ratio (case/control)
genetic parameters were used to identify the genes that influence the body size of pigs and …

[HTML][HTML] Practical approaches for knock-out gene editing in pigs

LD Ratner, GE La Motta, O Briski, DF Salamone… - Frontiers in …, 2021 - frontiersin.org
Pigs are an important resource for meat production and serve as a model for human
diseases. Due to their physiological and anatomical similarities to humans, these animals …

Integrating Computational and Biological Hemodynamic Approaches to Improve Modeling of Atherosclerotic Arteries

TNAM Vuong, M Bartolf‐Kopp, K Andelovic… - Advanced …, 2024 - Wiley Online Library
Atherosclerosis is the primary cause of cardiovascular disease, resulting in mortality,
elevated healthcare costs, diminished productivity, and reduced quality of life for individuals …

In vivo Evidence of Arterial Dynamic Properties Alteration in Atherosclerotic Rabbit

C Vayssettes-Courchay, C Ragonnet… - Journal of Vascular …, 2022 - karger.com
Objectives: Atherosclerosis severely damages the arterial wall. The aim of this study was to
assess in vivo, for the first time, arterial dynamic properties, reactivity, and stiffness in …