The purpose of this study was to identify a mechanism related to miRNA pathway which
plays a role in the anti-tumor effects of Diallyl disulfide. Alterations in miRNA expression …

Aims The aim of this study was (a) to determine the role of micro-223 (miR-223) in gastric
cancer and (b) to elucidate its regulatory mechanism on the FBXW7/hCdc4 gene. Materials …

Background Gastric cancer is an aggressive disease with a poor 5-year survival and large
global burden of disease. The disease is biologically and genetically heterogeneous with a …

Telomerase has attracted much attention as a universal cancer biomarker because
telomerase is overexpressed in more than 85% of human cancer cells while suppressed in …

The principle factors underlying gastric cancer (GC) development and outcomes are not well
characterized resulting in a paucity of validated therapeutic targets. To identify potential …

The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is frequently over-
expressed and serves as a prognostic marker in human cancers. However, little is known …

Background Intra-tumor heterogeneity is a potential cause for failure of targeted therapy in
gastric cancer, but the extent of heterogeneity of established (HER2) or potential (EGFR …

Background In the clinical practice of neoadjuvant chemotherapy, response markers are
very important. We aimed o investigate whether tumor markers CEA (carcino-embryonic …

Background Accumulating evidence demonstrated that long noncoding RNAs (lncRNAs)
played important regulatory roles in many cancer types. However, the role of lncRNAs in …

Malignancies of the peritoneal cavity are associated with a dismal prognosis. Systemic
chemotherapy is the gold standard for patients with unresectable peritoneal disease, but its …