Identification of key monocytes/macrophages related gene set of the early-stage abdominal aortic aneurysm by integrated bioinformatics analysis and experimental …

S Cheng, Y Liu, Y Jing, B Jiang, D Wang… - Frontiers in …, 2022 - frontiersin.org
Objective Abdominal aortic aneurysm (AAA) is a lethal peripheral vascular disease.
Inflammatory immune cell infiltration is a central part of the pathogenesis of AAA. It's critical …

[HTML][HTML] Immune response associated gene signatures in aortic dissection compared to aortic aneurysm

C Doppler, M Rezk, B Arbeithuber… - Frontiers in Bioscience …, 2024 - imrpress.com
Background: Thoracic aortic dissections (TAD) are life-threatening events mostly requiring
immediate surgical treatment. Although dissections mainly occur independently of thoracic …

k-Strong Inference Algorithm: A Hybrid Information Theory Based Gene Network Inference Algorithm

MÖ Cingiz - Molecular Biotechnology, 2023 - Springer
Gene networks allow researchers to understand the underlying mechanisms between
diseases and genes while reducing the need for wet lab experiments. Numerous gene …

Identification of the key genes and potential therapeutic compounds for abdominal aortic aneurysm based on a weighted correlation network analysis

L Li, K Kan, P Pallavi, M Keese - Biomedicines, 2022 - mdpi.com
Background: There is still an unmet need for therapeutic drugs for patients with an
abdominal aortic aneurysm (AAA), especially for candidates unsuitable for surgical or …

POU class 2 homeobox associating factor 1 (POU2AF1) participates in abdominal aortic aneurysm enlargement based on integrated bioinformatics analysis

J Meng, H Wen, X Li, B Luan, S Gong, J Wen… - …, 2021 - Taylor & Francis
Abdominal aortic aneurysm (AAA) is life-threatening, its natural course is progressively sac
expansion and rupture. Elegant studies have been conducted to investigate the molecular …

Comprehensive RNA expression analysis revealed biological functions of key gene sets and identified disease-associated cell types involved in rat traumatic brain …

Q Tang, M Song, R Zhao, X Han, L Deng… - Journal of Clinical …, 2022 - mdpi.com
Traumatic brain injury (TBI) is a worldwide public health concern without major therapeutic
breakthroughs over the past decades. Developing effective treatment options and improving …

Aortic Aneurysm: Finding the Right Target

E Kaschina - Biomedicines, 2023 - mdpi.com
This Special Issue of Biomedicines highlights many important scientific findings in aneurysm
research. The issue publishes a systematic, up-to-date review on aortic aneurysms (AAs) …

Gene Co-expression Network Analysis to Identify Key Genes Involved in the Development of Root-knot Nematode Meloidogyne Incognita

NO Mosioma - 2023 - erepository.uonbi.ac.ke
Plant-parasitic nematodes are a major cause of crop loss globally approximated at 150
billion dollars annually, and existing nematicides are toxic such that they offset the soil …

Ferroptosis-Related Genes in Hypertrophic Cardiomyopathy: Bioinformatics Insights and Immune Infiltration Interactions

M Shen, Y Chen, Y Cui, YK Shi - Available at SSRN 4865315 - papers.ssrn.com
Background Hypertrophic cardiomyopathy (HCM) is a common genetic heart disease that
can lead to severe heart failure and sudden death, yet its precise molecular mechanisms …