Compelling evidence exists for pervasive sex differences in pathological conditions,
including anxiety and depressive disorders, with females more than twice as likely to be …

Social anxiety disorder (SAD) is one of the most frequent anxiety disorders. The landmark
meta-analysis of functional neuroimaging studies by Etkin and Wager (2007) revealed …

Animal and human studies indicate that cannabidiol (CBD), a major constituent of cannabis,
has anxiolytic properties. However, no study to date has investigated the effects of this …

Brain imaging techniques allow the in vivo evaluation of the human brain, leading to a better
understanding of its anatomical, functional and metabolic substrate. The aim of this current …

The measurement of brain metabolites with magnetic resonance spectroscopy (MRS)
provides a unique perspective on the brain bases of neuropsychiatric disorders. As a context …

In 2000, Gorman et al. published a widely acknowledged revised version of their 1989
neuroanatomical hypothesis of panic disorder (PD). Herein, a 'fear network'was suggested …

Background The core domains of social anxiety disorder (SAD), generalized anxiety
disorder (GAD), panic disorder (PD) with and without agoraphobia (GA), and specific phobia …

The amygdala is often found to be abnormally recruited in social anxiety disorder (SAD)
patients. The question whether amygdala activation is primarily abnormal and affects other …

In social anxiety disorder (SAD), impairments in limbic/paralimbic structures are associated
with emotional dysregulation and inhibition of the medial prefrontal cortex (MPFC). Little is …

Anxiety disorders (AnxDs) are highly prevalent throughout the lifespan, with detrimental
effects on daily‐life functioning, somatic health, and quality of life. An emerging perspective …