Currently available NSAIDs represent a heterogeneous group of therapeutic agents
characterized by a variable benefit/risk profile. The development of a new class of selective …

Importance of the field: Studies have raised concern on the cardiovascular safety of NSAIDs.
We studied safety of NSAID therapy in a nationwide cohort of healthy individuals. Areas …

Use of some nonsteroidal anti‐inflammatory drugs (NSAIDs) is associated with increased
cardiovascular risk in several patient groups, but whether this excess risk exists in …

Purpose To describe the nationwide pattern of use of non‐steroidal anti‐inflammatory drugs
(NSAIDs) in the Danish population. Methods All Danish citizens aged 10 or above 1 January …

Non Steroidal anti-inflammatory Drugs (NSAIDs) are most commonly prescribed drugs
constituting more than 20% of all drug prescriptions. Prescription pattern study of NSAID was …

The present review indicates that there is no apparent well-tolerated therapeutic window for
associated cardiovascular risk and NSAID use in patients with prior MI. Further randomized …

Objective. Use of traditional nonsteroidal antiinflammatory drugs (tNSAID) increased after
rofecoxib withdrawal. tNSAID use is associated with increased gastrointestinal (GI) toxicity …

Purpose To examine the impact of safety warnings issued between 2005 and 2007 by the
Irish Medicines Board (IMB) on the rate of prescribing of clopidogrel, co‐amoxiclav …

Objective. To examine the incidence of gastrointestinal (GI) events in patients with
rheumatoid arthritis (RA) after the removal of rofecoxib from the market. Methods. Residents …

Bakgrunn Den 30.9. 2004 ble den selektive COX-2-hemmeren rofekoksib trukket tilbake fra
verdensmarkedet etter at flere studier hadde gitt holdepunkter for at bruk av rofekoksib …