AKIP1 accelerates glioblastoma progression through stabilizing EGFR expression

S Wan, C Liu, C Li, Z Wang, G Zhao, J Li, W Ran… - Oncogene, 2023 - nature.com
Abstract A Kinase Interacting Protein 1 (AKIP1) is found to be overexpressed in a variety of
human cancers and associated with patients' worse prognosis. Several studies have …

[HTML][HTML] E3 ubiquitin ligase HECTD3 is a tumor suppressor and mediates the polyubiquitination of SLC7A11 to promote ferroptosis in colon cancer

F Huang, Z Huang, Q Wei, G Liu, J Pu - Experimental Cell Research, 2023 - Elsevier
Homologous to the E6-associated protein carboxyl terminus domain containing 3 (HECTD3)
has been reported to play an essential role in biological processes, including drug …

OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway

M Ci, G Zhao, C Li, R Liu, X Hu, J Pan, Y Shen… - Cell Death & …, 2024 - nature.com
Abstract Glioblastoma, IDH-Wild type (GBM, CNS WHO Grade 4) is a highly heterogeneous
and aggressive primary malignant brain tumor with high morbidity, high mortality, and poor …

Modulatory Potential of Poly (ADP‐Ribose) Polymerase 1 (PARP1) in BRCA‐Mutated Tumors

V Munyembaraga, D Cyuzuzo, TNP Dao… - European Journal of …, 2024 - Wiley Online Library
Poly (ADP‐ribose) polymerase 1 is a versatile enzyme that is deeply involved in diverse
cellular processes. It exerts influence on pivotal activities such as DNA repair, transcriptional …

[HTML][HTML] The AEG-1-USP10-PARP1 axis confers radioresistance in esophageal squamous cell carcinoma via facilitating homologous recombination-dependent DNA …

X Zhao, Y Ma, J Li, X Sun, Y Sun, F Qu, X Shi, Y Xie… - Cancer letters, 2023 - Elsevier
Radiotherapy is the standard adjuvant treatment for esophageal squamous cell carcinoma
(ESCC), yet radioresistance remains a major obstacle leading to treatment failure and …

Predictive value of CCL2 in the prognosis and immunotherapy response of glioblastoma multiforme

L Deng, J Ren, B Li, Y Wang, N Jiang, Y Wang, H Cui - BMC genomics, 2023 - Springer
Background Glioblastoma multiforme (GBM) is the most common and lethal primary brain
tumor with a poor prognosis. The CC motif chemokine ligand 2 (CCL2) has shown abnormal …

TRIP13 regulates progression of gastric cancer through stabilising the expression of DDX21

G Zhang, R Yang, B Wang, Q Yan, P Zhao… - Cell Death & …, 2024 - nature.com
GC (Gastric cancer) is one of the most common malignant tumours, with over 95% of gastric
cancer patients being adenocarcinoma and most gastric cancer patients having no apparent …

Molecular prognostic of nine parthanatos death‐related genes in glioma, particularly in COL8A1 identification

S Fan, H Li, K Liu - Journal of Neurochemistry, 2024 - Wiley Online Library
Post‐operative progression and chemotherapy resistance are the main causes of treatment
failure in glioma patients. There is a lack of ideal prediction models for post‐operative …

Targeting MCL1 with Sanggenon C overcomes MCL1-driven adaptive chemoresistance via dysregulation of autophagy and endoplasmic reticulum stress in cervical …

W Sun, H Cai, K Zhang, H Cui, E Zhao - Phytomedicine, 2024 - Elsevier
Background Cervical cancer ranks as one of the most prevalent malignancies among
women worldwide and poses a significant threat to health and quality of life. MCL1 is an …

PHF12 regulates HDAC1 to promote tumorigenesis via EGFR/AKT signaling pathway in non-small cell lung cancer

Y Kong, R Jiang, H Zhou, M Ge, H Lin, Y Wang… - Journal of Translational …, 2024 - Springer
Background Lung cancer stands as the second most prevalent malignant neoplasm
worldwide. Addressing the underlying mechanisms propelling the progression of non-small …