It has been established that 4.4 to 20% of the general population suffers from a major
depressive disorder (MDD), which is frequently associated with a dysregulation of normal …

The COVID-19 pandemic has resulted in enormous losses in terms of human lives and
economy in United States. The outbreak has been continuing to heavily impact the mental …

Bipolar disorder is heterogeneous in phenomenology, illness trajectory, and response to
treatment. Despite evidence for the efficacy of multimodality interventions, the majority of …

Background By affecting the internal timing mechanisms of the brain, light regulates human
physiology and behavior, perhaps most notably the sleep–wake cycle. Humans spend over …

Children with Autism Spectrum Disorder (ASD) are at an increased risk for sleep
disturbances, and studies indicate that between 50 and 80% of children with ASD …

An association with circadian clock function and pathophysiology of aging, major depressive
disorder (MDD), and Alzheimer's disease (AD) is well established and has been proposed …

Background: Circadian rhythm disruption underlies the pathophysiology of psychiatric
disorders, especially depression. Both pharmacological and non-pharmacological strategies …

Abstract Purpose of Review Disruptions in circadian rhythms are believed to underlie the
illness course of bipolar disorder (BD). This review evaluates recent studies on the treatment …

Rapidly accumulating data from mobile assessments are facilitating our ability to track
patterns of emotions, behaviors, biologic rhythms, and their contextual influences in real …

Background The poor prognostic of Bipolar disorders (BD) is closely linked to deaths by
suicide. Sleep and circadian abnormalities are observed during all phases of BD and are …