Rapidly accumulating data from mobile assessments are facilitating our ability to track
patterns of emotions, behaviors, biologic rhythms, and their contextual influences in real …

Objectives People with bipolar disorder (BD) spend more time depressed than
manic/hypomanic, and depression is associated with greater impairments in psychosocial …

The ventral tegmental area (VTA), an important source of dopamine, regulates goal-and
reward-directed and social behaviors, wakefulness, and sleep. Hyperactivation of dopamine …

ANK3 is a leading bipolar disorder (BD) candidate gene in humans and provides a unique
opportunity for studying epilepsy-BD comorbidity. Previous studies showed that deletion of …

Improvement of sleep is a central treatment goal for patients in a manic state. Blue‐blocking
(BB) glasses as adjunctive treatment hasten overall recovery from mania. This method is an …

Sleep problems are highly prevalent in bipolar disorder (BD) and constitute an important
therapeutic focus in this population: They are highly impairing and distressing, are an area …

Highlights•Sleep disturbance in bipolar disorder is common and associated with impaired
functioning.•Sleep disturbance may interfere with adequate response to …

Background It is estimated that up to 50% of people with bipolar disorder (BD) also have
comorbid post-traumatic stress disorder (PTSD). However, little is known about the …

Dysregulated sleep is commonly reported in individuals with neuropsychiatric disorders,
including schizophrenia (SCZ) and bipolar disorder (BPD). Physiology and pathogenesis of …

Bipolar disorders have an onset in late adolescence or early adulthood and patients may
experience alternating episodes of mania and depression, with euthymic periods …