[HTML][HTML] The human mycobiome in chronic respiratory diseases: current situation and future perspectives

J de Dios Caballero, R Cantón, M Ponce-Alonso… - Microorganisms, 2022 - mdpi.com
Microbes play an important role in the pathogenesis of chronic lung diseases, such as
chronic obstructive pulmonary disease, cystic fibrosis, non-cystic fibrosis bronchiectasis, and …

Infections after organ transplantation and immune response

A Elalouf - Transplant Immunology, 2023 - Elsevier
Organ transplantation has provided another chance of survival for end-stage organ failure
patients. Yet, transplant rejection is still a main challenging factor. Immunosuppressive drugs …

[HTML][HTML] CF-Seq, an accessible web application for rapid re-analysis of cystic fibrosis pathogen RNA sequencing studies

SL Neff, TH Hampton, C Puerner, L Cengher, G Doing… - Scientific Data, 2022 - nature.com
Researchers studying cystic fibrosis (CF) pathogens have produced numerous RNA-seq
datasets which are available in the gene expression omnibus (GEO). Although these studies …

[HTML][HTML] Fungal microbiota dynamics and its geographic, age and gender variability in patients with cystic fibrosis

S Martínez-Rodríguez, V Friaza… - Clinical Microbiology …, 2023 - Elsevier
Objectives In cystic fibrosis (CF), there is a predisposition to bronchial colonization by
potentially pathogenic microorganisms, such as fungi. Our aims were to describe the …

Emerging fungal threats in cystic fibrosis

C Schwarz, P Eschenhagen, JP Bouchara - Mycopathologia, 2021 - Springer
In the past three decades, fungal respiratory colonization and fungal respiratory infections
increasingly raised concern in cystic fibrosis (CF). Reasons for this are a better knowledge of …

[HTML][HTML] Association between Cystic Fibrosis exacerbations, lung function, T2 inflammation and microbiological colonization

D Albon, L Zhang, J Patrie, M Jones, ZG Li… - Allergy, Asthma & …, 2023 - Springer
Abstract Background The Cystic Fibrosis Foundation Patient Registry (CFFPR) reports a
high prevalence of asthma (34.6%) in people with Cystic Fibrosis (PwCF). While our current …

Fungal Colonization of the Airways of Patients with Cystic Fibrosis: the Role of the Environmental Reservoirs

K Ravenel, H Guegan, A Gastebois, JP Bouchara… - Mycopathologia, 2024 - Springer
Filamentous fungi frequently colonize the airways of patients with cystic fibrosis and may
cause severe diseases, such as the allergic bronchopulmonary aspergillosis. The most …

[HTML][HTML] Isolation of Exophiala dermatitidis is not associated with worse clinical outcomes during acute pulmonary exacerbations in cystic fibrosis

DH Tewkesbury, E Looi, PJ Barry… - Journal of medical …, 2022 - microbiologyresearch.org
Introduction. The black yeast Exophiala dermatitidis has been isolated in respiratory
samples from people with cystic fibrosis (CF). However, adequate detection may require …

[HTML][HTML] A Lateral-Flow Device for the Rapid Detection of Scedosporium Species

GE Davies, CR Thornton - Diagnostics, 2024 - mdpi.com
Scedosporium species are human pathogenic fungi, responsible for chronic, localised, and
life-threatening disseminated infections in both immunocompetent and …

Clinical pharmacokinetics and dose recommendations for posaconazole gastroresistant tablets in children with cystic fibrosis

S Bentley, JC Davies, S Gastine… - Journal of …, 2021 - academic.oup.com
Objectives To investigate the population pharmacokinetics of posaconazole gastroresistant
tablets in children with cystic fibrosis (CF) and perform simulations to recommend optimal …