Review of advances in electrospinning-based strategies for spinal cord regeneration

Y Li, T Dong, Z Li, S Ni, F Zhou, OA Alimi, S Chen… - Materials Today …, 2022 - Elsevier
Spinal cord injury (SCI) is a devastating neurological condition, commonly leading to
physical and mental deficiencies, pain, other complications, and even death. Most recently …

[HTML][HTML] The immune microenvironment and tissue engineering strategies for spinal cord regeneration

Y Feng, Y Peng, J Jie, Y Yang, P Yang - Frontiers in Cellular …, 2022 - frontiersin.org
Regeneration of neural tissue is limited following spinal cord injury (SCI). Successful
regeneration of injured nerves requires the intrinsic regenerative capability of the neurons …

Restoration of spinal cord biophysical microenvironment for enhancing tissue repair by injury-responsive smart hydrogel

C Fan, W Yang, L Zhang, H Cai, Y Zhuang, Y Chen… - Biomaterials, 2022 - Elsevier
Spinal cord injury (SCI) represents a central nervous system disaster, resulting in the
destruction of spinal cord structure and function and the formation of an adverse …

[HTML][HTML] Recent advances in endogenous neural stem/progenitor cell manipulation for spinal cord injury repair

J Li, W Luo, C Xiao, J Zhao, C Xiang, W Liu, R Gu - Theranostics, 2023 - ncbi.nlm.nih.gov
Traumatic spinal cord injury (SCI) can cause severe neurological impairments. Clinically
available treatments are quite limited, with unsatisfactory remediation effects. Residing …

Mechanics-electro-adaptive multifunctional bioactive nanocomposites hydrogel for inducing spinal cord regeneration

M Wang, C Wang, M Chen, M Luo, Q Chen… - Chemical Engineering …, 2022 - Elsevier
Traumatic spinal cord injury (SCI) is one of the most serious injuries, which will cause severe
sensory and motor obstacles. The current effective treatment methods remain a worldwide …

Biomaterial-mediated factor delivery for spinal cord injury treatment

F Pinelli, F Pizzetti, V Veneruso, E Petillo, M Raghunath… - Biomedicines, 2022 - mdpi.com
Spinal cord injury (SCI) is an injurious process that begins with immediate physical damage
to the spinal cord and associated tissues during an acute traumatic event. However, the …

Multifunctional hydrogel modulates the immune microenvironment to improve allogeneic spinal cord tissue survival for complete spinal cord injury repair

X Gao, Z You, Y Li, X Kang, W Yang, H Wang, T Zhang… - Acta Biomaterialia, 2023 - Elsevier
Transplantation of allogeneic adult spinal cord tissues (aSCTs) to replace the injured spinal
cord, serves as a promising strategy in complete spinal cord injury (SCI) repair. However, in …

Cell Development Enhanced Bionic Silk Hydrogel on Remodeling Immune Pathogenesis of Spinal Cord Injury via M2 Polarization of Microglial

J Ling, T Huang, R Wu, C Ma, G Lin… - Advanced Functional …, 2023 - Wiley Online Library
Due to the complex spatial‐temporal pathophysiology of spinal cord injury (SCI), effective
modulation of SCI‐specific inflammatory pathogenesis to achieve desirable therapeutic …

A decellularized spinal cord extracellular matrix-gel/GelMA hydrogel three-dimensional composite scaffold promotes recovery from spinal cord injury via synergism …

W He, X Zhang, X Li, D Ju, T Mao, Y Lu, Y Gu… - Journal of Materials …, 2022 - pubs.rsc.org
Spinal cord injury (SCI), as a serious disabling disease, is still haunted by lacking of effective
treatments. We previously found that transplantation of menstrual blood-derived …

Therapeutic effect of biomimetic scaffold loaded with human amniotic epithelial cell-derived neural-like cells for spinal cord injury

C Qiu, Y Sun, J Li, Y Xu, J Zhou, C Qiu, S Zhang, Y He… - Bioengineering, 2022 - mdpi.com
Spinal cord injury (SCI) results in devastating consequences for the motor and sensory
function of patients due to neuronal loss and disrupted neural circuits, confronting poor …