[HTML][HTML] Pharmacotherapies in dupuytren disease: current and novel strategies

AG Lambi, SN Popoff, P Benhaim, MF Barbe - The Journal of hand surgery, 2023 - Elsevier
Dupuytren disease is a benign, progressive fibroproliferative disorder of the hands. To date,
only one pharmacotherapy (clostridial collagenase) has been approved for use in …

[HTML][HTML] The oncogenic landscape of the idiopathic pulmonary fibrosis: a narrative review

GM Stella, V D'Agnano, D Piloni… - Translational Lung …, 2022 - ncbi.nlm.nih.gov
Methods A systematic literature review was performed to identify all relevant data. The
examined databases were Scopus, Web of Science, Cochrane, Google Scholar, and …

Nerve transfer for restoration of lower motor neuron-lesioned bladder, urethral and anal sphincter function. Part 4: Effectiveness of the motor reinnervation

E Tiwari, DS Porreca, AS Braverman… - American Journal …, 2024 - journals.physiology.org
In pilot work, we showed that somatic nerve transfers can restore motor function in long-term
decentralized dogs. We continue to explore the effectiveness of motor reinnervation in 30 …

[HTML][HTML] A single-cell network-based drug repositioning strategy for post-COVID-19 pulmonary fibrosis

A Li, JY Chen, CL Hsu, YJ Oyang, HC Huang, HF Juan - Pharmaceutics, 2022 - mdpi.com
Post-COVID-19 pulmonary fibrosis (PCPF) is a long-term complication that appears in some
COVID-19 survivors. However, there are currently limited options for treating PCPF patients …

IBPA a mutual prodrug of ibuprofen and acetaminophen alleviates inflammation, immune dysregulation and fibrosis in preclinical models of systemic sclerosis

AR de Almeida, FJBM Junior, AT Dantas… - International …, 2024 - Elsevier
Systemic sclerosis (SSc) is a devastating autoimmune illness with a wide range of clinical
symptoms, including vascular abnormalities, inflammation, and persistent and progressive …

[HTML][HTML] Let's Focus on the Fibrosis in Dupuytren Disease: Cell Communication Network Factor 2 as a Novel Target

AG Lambi, NT Morrell, SN Popoff, P Benhaim… - Journal of Hand Surgery …, 2023 - Elsevier
Dupuytren disease is a progressive, benign fibroproliferative disorder of the hands that can
lead to debilitating hand contractures. Once symptomatic, treatment involves either surgical …

Computational and in vitro screening validates the repositioning potential of Coxibs as anti-fibrotic agents

S Karande, B Das, SS Acharya, A Kumar… - Journal of …, 2024 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease with a survival rate of< 5
years. The TGF-β plays a significant role in the progression and severity of IPF. The TGF-β …

Let's Focus on the Fibrosis: Targeting CCN2 in Dupuytren's Disease

AG Lambi, R Dahlberg, T Holy… - Western Journal of …, 2023 - digitalrepository.unm.edu
Dupuytren's disease is a progressive, benign fibroproliferative disorder of the hands that can
lead to debilitating hand contractures. Once symptomatic, treatment involves either surgical …

[HTML][HTML] Skin Gene Expression Profiles in Systemic Sclerosis: From Clinical Stratification to Precision Medicine

D Benfaremo, S Agarbati, M Mozzicafreddo… - International Journal of …, 2023 - mdpi.com
Systemic sclerosis, also known as scleroderma or SSc, is a condition characterized by
significant heterogeneity in clinical presentation, disease progression, and response to …