Immunotherapies for hepatocellular carcinoma

JM Llovet, F Castet, M Heikenwalder… - Nature reviews Clinical …, 2022 - nature.com
Liver cancer, more specifically hepatocellular carcinoma (HCC), is the second leading
cause of cancer-related death and its incidence is increasing globally. Around 50% of …

[HTML][HTML] Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors

DQ Huang, P Mathurin, H Cortez-Pinto… - Nature reviews …, 2023 - nature.com
Heavy alcohol consumption is a major cause of morbidity and mortality. Globally, alcohol per-
capita consumption rose from 5.5 litres in 2005 to 6.4 litres in 2016 and is projected to …

[HTML][HTML] Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer

DQ Huang, AG Singal, Y Kono, DJH Tan, HB El-Serag… - Cell metabolism, 2022 - cell.com
Liver cancer epidemiology is changing due to increasing alcohol consumption, rising
prevalence of obesity, and advances in hepatitis B virus (HBV) and hepatitis C virus (HCV) …

Hepatobiliary cancers, version 2.2021, NCCN clinical practice guidelines in oncology

AB Benson, MI D'Angelica, DE Abbott… - Journal of the National …, 2021 - jnccn.org
The NCCN Guidelines for Hepatobiliary Cancers focus on the screening, diagnosis, staging,
treatment, and management of hepatocellular carcinoma (HCC), gallbladder cancer, and …

Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification

S Chidambaranathan-Reghupaty, PB Fisher… - Advances in cancer …, 2021 - Elsevier
Hepatocellular carcinoma (HCC), the primary malignancy of hepatocytes, is a diagnosis with
bleak outcome. According to National Cancer Institute's SEER database, the average five …

Global epidemiology and genetics of hepatocellular carcinoma

MR Toh, EYT Wong, SH Wong, AWT Ng, LH Loo… - Gastroenterology, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is one of the leading cancers worldwide. Classically, HCC
develops in genetically susceptible individuals who are exposed to risk factors, especially in …

[HTML][HTML] Pathophysiological aspects of alcohol metabolism in the liver

J Hyun, J Han, C Lee, M Yoon, Y Jung - International journal of molecular …, 2021 - mdpi.com
Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic
or binge consumption of alcohol. The liver is the major organ that metabolizes alcohol; …

[HTML][HTML] Etiology of hepatocellular carcinoma: special focus on fatty liver disease

D Suresh, AN Srinivas, DP Kumar - Frontiers in Oncology, 2020 - frontiersin.org
Hepatocellular Carcinoma (HCC) is a highly aggressive cancer with mortality running
parallel to its incidence and has limited therapeutic options. Chronic liver inflammation and …

[HTML][HTML] Prevention of NAFLD-associated HCC: Role of lifestyle and chemoprevention

NF Lange, P Radu, JF Dufour - Journal of hepatology, 2021 - Elsevier
In many countries worldwide, the burden of hepatocellular carcinoma (HCC) associated with
non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) is …

MicroRNA‐214‐3p enhances erastin‐induced ferroptosis by targeting ATF4 in hepatoma cells

T Bai, R Liang, R Zhu, W Wang… - Journal of cellular …, 2020 - Wiley Online Library
Primary liver cancer is the second most frequent cause of cancer‐related deaths.
Ferroptosis, a recognized form of regulated cell death, recently gains attention. MicroRNA …