Novel therapeutic hybrid systems using hydrogels and nanotechnology: a focus on nanoemulgels for the treatment of skin diseases
K Sghier, M Mur, F Veiga, AC Paiva-Santos, PC Pires - Gels, 2024 - mdpi.com
Topical and transdermal drug delivery are advantageous administration routes, especially
when treating diseases and conditions with a skin etiology. Nevertheless, conventional …
when treating diseases and conditions with a skin etiology. Nevertheless, conventional …
Impact of TRPV1 on Pathogenesis and Therapy of Neurodegenerative Diseases
W Wang, T Sun - Molecules, 2023 - mdpi.com
Transient receptor potential vanilloid 1 (TRPV1) is a transmembrane and non-selective
cation channel protein, which can be activated by various physical and chemical stimuli …
cation channel protein, which can be activated by various physical and chemical stimuli …
[HTML][HTML] Taming neuroinflammation in Alzheimer's disease: The protective role of phytochemicals through the gut− brain axis
Alzheimer's disease (AD) is a progressive degenerative neurological condition
characterized by cognitive decline, primarily affecting memory and logical thinking, attributed …
characterized by cognitive decline, primarily affecting memory and logical thinking, attributed …
Xenobiotic Exposure and Migraine-Associated Signaling: A Multimethod Experimental Study Exploring Cellular Assays in Combination with Ex Vivo and In Vivo …
RH Rasmussen, SL Christensen… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Mechanisms for how environmental chemicals might influence pain has
received little attention. Epidemiological studies suggest that environmental factors such as …
received little attention. Epidemiological studies suggest that environmental factors such as …
Computational methods in glaucoma research: current status and future outlook
MJ Kim, CA Martin, J Kim, MM Jablonski - Molecular Aspects of Medicine, 2023 - Elsevier
Advancements in computational techniques have transformed glaucoma research, providing
a deeper understanding of genetics, disease mechanisms, and potential therapeutic targets …
a deeper understanding of genetics, disease mechanisms, and potential therapeutic targets …
An aqueous Commiphora myrrha extract ameliorates paclitaxel-induced peripheral neuropathic pain in mice
A Al-Romaiyan, A Barakat, L Jose… - Frontiers in …, 2023 - frontiersin.org
Background: Chemotherapy-induced neuropathic pain (CINP) is a debilitating side effect in
individuals undergoing cancer treatment. Treatment of CINP with the current available …
individuals undergoing cancer treatment. Treatment of CINP with the current available …
Inhibition potential against acetylcholinesterase of commercial and extracts of capsaicin and dihydrocapsaicin by in vitro and in silico studies
P Mansalai, N Intanon, A Payaka… - Process …, 2024 - Elsevier
The present research investigates the amount of capsaicin and dihydrocapsaicin in three
parts of chili extracts (pericarp, seeds, and placenta). Moreover, inhibition potential of …
parts of chili extracts (pericarp, seeds, and placenta). Moreover, inhibition potential of …
TRPV1 channel in the pathophysiology of epilepsy and its potential as a molecular target for the development of new antiseizure drug candidates
K Socała, M Jakubiec, M Abram, J Mlost… - Progress in …, 2024 - Elsevier
Identification of transient receptor potential cation channel, subfamily V member 1 (TRPV1),
also known as capsaicin receptor, in 1997 was a milestone achievement in the research on …
also known as capsaicin receptor, in 1997 was a milestone achievement in the research on …
Multiple effects of spicy flavors on neurological diseases through the intervention of TRPV1: a critical review
B Hu, H Wang, H Liang, N Ma, D Wu… - Critical Reviews in …, 2024 - Taylor & Francis
The spicy properties of foods are contributed by various spicy flavor substances (SFs) such
as capsaicin, piperine, and allicin. Beyond their distinctive sensory characteristics, SFs also …
as capsaicin, piperine, and allicin. Beyond their distinctive sensory characteristics, SFs also …
[HTML][HTML] Capsaicin Modulates Hepatic and Intestinal Inflammation and Oxidative Stress by Regulating the Colon Microbiota
X Pang, X Wei, Y Wu, S Nan, J Feng, F Wang, M Yao… - Antioxidants, 2024 - mdpi.com
We aimed to investigate the role of capsaicin (CAP) in modulating lipopolysaccharide (LPS)-
induced hepatic and intestinal inflammation, oxidative stress, and its colonic microflora in …
induced hepatic and intestinal inflammation, oxidative stress, and its colonic microflora in …