Epigenetics across the human lifespan

RR Kanherkar, N Bhatia-Dey, AB Csoka - Frontiers in cell and …, 2014 - frontiersin.org
Epigenetics has the potential to explain various biological phenomena that have heretofore
defied complete explication. This review describes the various types of endogenous human …

Epigenetics and allergy: from basic mechanisms to clinical applications

DP Potaczek, H Harb, S Michel, BA Alhamwe… - …, 2017 - Taylor & Francis
Allergic diseases are on the rise in the Western world and well-known allergy-protecting and-
driving factors such as microbial and dietary exposure, pollution and smoking mediate their …

An update of epigenetic drugs for the treatment of cancers and brain diseases: a comprehensive review

Z Sahafnejad, S Ramazi, A Allahverdi - Genes, 2023 - mdpi.com
Epigenetics has long been recognized as a significant field in biology and is defined as the
investigation of any alteration in gene expression patterns that is not attributed to changes in …

Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases

B Paul, S Barnes, W Demark-Wahnefried, C Morrow… - Clinical …, 2015 - Springer
Epigenetic modulation of gene activity occurs in response to non-genetic factors such as
body weight status, physical activity, dietary factors, and environmental toxins. In addition …

Dietary phytochemicals in breast cancer research: anticancer effects and potential utility for effective chemoprevention

A Kapinova, P Kubatka, O Golubnitschaja… - … health and preventive …, 2018 - Springer
Cancerous tissue transformation developing usually over years or even decades of life is a
highly complex process involving strong stressors damaging DNA, chronic inflammation …

Causes of genome instability: the effect of low dose chemical exposures in modern society

SAS Langie, G Koppen, D Desaulniers… - …, 2015 - academic.oup.com
Genome instability is a prerequisite for the development of cancer. It occurs when genome
maintenance systems fail to safeguard the genome's integrity, whether as a consequence of …

Non-nutritive sweeteners and their implications on the development of metabolic syndrome

I Liauchonak, B Qorri, F Dawoud, Y Riat, MR Szewczuk - Nutrients, 2019 - mdpi.com
Individuals widely use non-nutritive sweeteners (NNS) in attempts to lower their overall daily
caloric intake, lose weight, and sustain a healthy diet. There are insufficient scientific data …

New insight into microRNA functions in cancer: oncogene–microRNA–tumor suppressor gene network

K Zhou, M Liu, Y Cao - Frontiers in molecular biosciences, 2017 - frontiersin.org
Tumorigenesis is a multi-step and complex process with multi-factors involved. Deregulated
oncogenes and tumor suppressor genes (TSGs) induced by genetic and epigenetic factors …

Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1 …

R Kala, HN Shah, SL Martin, TO Tollefsbol - BMC cancer, 2015 - Springer
Background Nutrition is believed to be a primary contributor in regulating gene expression
by affecting epigenetic pathways such as DNA methylation and histone modification …

Current insights into oral cancer epigenetics

AI Irimie, C Ciocan, D Gulei, N Mehterov… - International journal of …, 2018 - mdpi.com
Epigenetic modifications have emerged into one of the cancer hallmarks, replacing the
concept of malignant pathologies as being solely genetic-based conditions. The epigenetic …