[HTML][HTML] Epigenetics of human diseases and scope in future therapeutics
Epigenetics is the study of nucleotide modifications that are heritable and act as regulatory
mechanisms without changing the nucleotide sequence of the genome. Exogenous cues …
mechanisms without changing the nucleotide sequence of the genome. Exogenous cues …
miR-124 functions as a tumor suppressor in the endometrial carcinoma cell line HEC-1B partly by suppressing STAT3
Y Li, Z Zhang, X Liu, T Huang, W He, Y Shen… - Molecular and cellular …, 2014 - Springer
MicroRNAs (miRNAs) play an important role in the development and progression of
endometrial carcinoma (EC). Recently, several studies have shown that microRNA-124 (miR …
endometrial carcinoma (EC). Recently, several studies have shown that microRNA-124 (miR …
MiRNA153 reduces effects of chemotherapeutic agents or small molecular kinase inhibitor in HCC cells
Y Chen, F Feng, X Gao, C Wang, H Sun… - Current Cancer Drug …, 2015 - ingentaconnect.com
MicroRNA-153 (miR-153) is considered to be a tumor regulator. Silencing of miR-153
expression induced apoptosis in breast cancer cells. Data on mechanism suggest that up …
expression induced apoptosis in breast cancer cells. Data on mechanism suggest that up …
[HTML][HTML] The plasticizer bisphenol a perturbs the hepatic epigenome: a systems level analysis of the miRNome
L Renaud, WA da Silveira, ES Hazard, J Simpson… - Genes, 2017 - mdpi.com
Ubiquitous exposure to bisphenol A (BPA), an endocrine disruptor (ED), has raised
concerns for both human and ecosystem health. Epigenetic factors, including microRNAs …
concerns for both human and ecosystem health. Epigenetic factors, including microRNAs …
Diet phytochemicals and cutaneous carcinoma chemoprevention: A review
S Wang, P Shen, J Zhou, Y Lu - Pharmacological research, 2017 - Elsevier
Cutaneous carcinoma, which has occupied a peculiar place among worldwide populations,
is commonly responsible for the considerably increasing morbidity and mortality rates …
is commonly responsible for the considerably increasing morbidity and mortality rates …
[HTML][HTML] Overexpression of miR-140 inhibits proliferation of osteosarcoma cells via suppression of histone deacetylase 4
Q Xiao, L Huang, Z Zhang, X Chen, J Luo… - Oncology …, 2017 - ncbi.nlm.nih.gov
Abstract miRNAs play a pivotal role in the development and progression of osteosarcoma
(OS). Previous studies indicated that miR-140 acts as a tumor suppressor in many cancers …
(OS). Previous studies indicated that miR-140 acts as a tumor suppressor in many cancers …
[HTML][HTML] miR-485 acts as a tumor suppressor by inhibiting cell growth and migration in breast carcinoma T47D cells
M Anaya-Ruiz, C Bandala… - Asian Pacific Journal of …, 2013 - koreascience.kr
MicroRNAs (miRNAs) are small, non-coding RNAs (18-25 nucleotides) that post-
transcriptionally modulate gene expression by negatively regulating the stability or …
transcriptionally modulate gene expression by negatively regulating the stability or …
Targeting of cell cycle and let-7a/STAT3 pathway by niclosamide inhibits proliferation, migration and invasion in oral squamous cell carcinoma cells
X Li, R Ding, Z Han, Z Ma, Y Wang - Biomedicine & Pharmacotherapy, 2017 - Elsevier
The low median survival rate of oral squamous cell carcinoma (OSCC) is associated with
chemotherapeutic resistance. Niclosamide is an oral anti-helminthic drug, its anti-cancer …
chemotherapeutic resistance. Niclosamide is an oral anti-helminthic drug, its anti-cancer …
Genome-wide sequencing reveals MicroRNAs downregulated in cerebral cavernous malformations
Cerebral cavernous malformations (CCM) are vascular lesions associated with loss-of-
function mutations in one of the three genes encoding KRIT1 (CCM1), CCM2, and PDCD10 …
function mutations in one of the three genes encoding KRIT1 (CCM1), CCM2, and PDCD10 …
[HTML][HTML] DNMT1/miR-200a/GOLM1 signaling pathway regulates lung adenocarcinoma cells proliferation
L Yang, P Luo, Q Song, X Fei - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Objectives Lung adenocarcinoma (LAD) comprises about 80% of all diagnosed lung
cancers. However, the underlying regulatory mechanism of LAD cell proliferation is largely …
cancers. However, the underlying regulatory mechanism of LAD cell proliferation is largely …