[HTML][HTML] Epigenetics of human diseases and scope in future therapeutics

MB Shamsi, AS Firoz, SN Imam, N Alzaman… - Journal of Taibah …, 2017 - Elsevier
Epigenetics is the study of nucleotide modifications that are heritable and act as regulatory
mechanisms without changing the nucleotide sequence of the genome. Exogenous cues …

miR-124 functions as a tumor suppressor in the endometrial carcinoma cell line HEC-1B partly by suppressing STAT3

Y Li, Z Zhang, X Liu, T Huang, W He, Y Shen… - Molecular and cellular …, 2014 - Springer
MicroRNAs (miRNAs) play an important role in the development and progression of
endometrial carcinoma (EC). Recently, several studies have shown that microRNA-124 (miR …

MiRNA153 reduces effects of chemotherapeutic agents or small molecular kinase inhibitor in HCC cells

Y Chen, F Feng, X Gao, C Wang, H Sun… - Current Cancer Drug …, 2015 - ingentaconnect.com
MicroRNA-153 (miR-153) is considered to be a tumor regulator. Silencing of miR-153
expression induced apoptosis in breast cancer cells. Data on mechanism suggest that up …

[HTML][HTML] The plasticizer bisphenol a perturbs the hepatic epigenome: a systems level analysis of the miRNome

L Renaud, WA da Silveira, ES Hazard, J Simpson… - Genes, 2017 - mdpi.com
Ubiquitous exposure to bisphenol A (BPA), an endocrine disruptor (ED), has raised
concerns for both human and ecosystem health. Epigenetic factors, including microRNAs …

Diet phytochemicals and cutaneous carcinoma chemoprevention: A review

S Wang, P Shen, J Zhou, Y Lu - Pharmacological research, 2017 - Elsevier
Cutaneous carcinoma, which has occupied a peculiar place among worldwide populations,
is commonly responsible for the considerably increasing morbidity and mortality rates …

[HTML][HTML] Overexpression of miR-140 inhibits proliferation of osteosarcoma cells via suppression of histone deacetylase 4

Q Xiao, L Huang, Z Zhang, X Chen, J Luo… - Oncology …, 2017 - ncbi.nlm.nih.gov
Abstract miRNAs play a pivotal role in the development and progression of osteosarcoma
(OS). Previous studies indicated that miR-140 acts as a tumor suppressor in many cancers …

[HTML][HTML] miR-485 acts as a tumor suppressor by inhibiting cell growth and migration in breast carcinoma T47D cells

M Anaya-Ruiz, C Bandala… - Asian Pacific Journal of …, 2013 - koreascience.kr
MicroRNAs (miRNAs) are small, non-coding RNAs (18-25 nucleotides) that post-
transcriptionally modulate gene expression by negatively regulating the stability or …

Targeting of cell cycle and let-7a/STAT3 pathway by niclosamide inhibits proliferation, migration and invasion in oral squamous cell carcinoma cells

X Li, R Ding, Z Han, Z Ma, Y Wang - Biomedicine & Pharmacotherapy, 2017 - Elsevier
The low median survival rate of oral squamous cell carcinoma (OSCC) is associated with
chemotherapeutic resistance. Niclosamide is an oral anti-helminthic drug, its anti-cancer …

Genome-wide sequencing reveals MicroRNAs downregulated in cerebral cavernous malformations

S Kar, KK Bali, A Baisantry, R Geffers, A Samii… - Journal of Molecular …, 2017 - Springer
Cerebral cavernous malformations (CCM) are vascular lesions associated with loss-of-
function mutations in one of the three genes encoding KRIT1 (CCM1), CCM2, and PDCD10 …

[HTML][HTML] DNMT1/miR-200a/GOLM1 signaling pathway regulates lung adenocarcinoma cells proliferation

L Yang, P Luo, Q Song, X Fei - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Objectives Lung adenocarcinoma (LAD) comprises about 80% of all diagnosed lung
cancers. However, the underlying regulatory mechanism of LAD cell proliferation is largely …