Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment
VMM Giménez, F Inserra, CD Tajer, J Mariani, L Ferder… - Life sciences, 2020 - Elsevier
COVID-19 pandemic has a high mortality rate and is affecting practically the entire world
population. The leading cause of death is severe acute respiratory syndrome as a …
population. The leading cause of death is severe acute respiratory syndrome as a …
The dual impact of ACE2 in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions
The novel corona virus disease has shaken the entire world with its deadly effects and rapid
transmission rates, posing a significant challenge to the healthcare authorities to develop …
transmission rates, posing a significant challenge to the healthcare authorities to develop …
Kidney damage caused by obesity and its feasible treatment drugs
M Wang, Z Wang, Y Chen, Y Dong - International journal of molecular …, 2022 - mdpi.com
The rapid growth of obesity worldwide has made it a major health problem, while the
dramatic increase in the prevalence of obesity has had a significant impact on the …
dramatic increase in the prevalence of obesity has had a significant impact on the …
Circadian clocks of the kidney: function, mechanism, and regulation
HM Costello, JG Johnston, A Juffre… - Physiological …, 2022 - journals.physiology.org
An intrinsic cellular circadian clock is located in nearly every cell of the body. The peripheral
circadian clocks within the cells of the kidney contribute to the regulation of a variety of renal …
circadian clocks within the cells of the kidney contribute to the regulation of a variety of renal …
Elderly as a high-risk group during COVID-19 pandemic: effect of circadian misalignment, sleep dysregulation and melatonin administration
The association of age with a higher vulnerability to COVID-19 infection is a subject of major
importance. Several factors, including higher stress due to social isolation, diminished …
importance. Several factors, including higher stress due to social isolation, diminished …
Melatonin as a potential approach to anxiety treatment
Anxiety disorders are the most common mental diseases. Anxiety and the associated
physical symptoms may disturb social and occupational life and increase the risk of somatic …
physical symptoms may disturb social and occupational life and increase the risk of somatic …
Developmental origins of kidney disease: why oxidative stress matters?
The “developmental origins of health and disease” theory indicates that many adult-onset
diseases can originate in the earliest stages of life. The developing kidney has emerged as …
diseases can originate in the earliest stages of life. The developing kidney has emerged as …
Exosomes and melatonin: Where their destinies intersect
Cell-to-cell communication is a broad and complex process associated with regular stimuli
to maintain healthy cell interactions. One of the agents capable of cellular communication is …
to maintain healthy cell interactions. One of the agents capable of cellular communication is …
TGF-β1, NAG-1, and antioxidant enzymes expression alterations in Cisplatin-induced nephrotoxicity in a rat model: Comparative modulating role of Melatonin, Vit. E …
Cisplatin (CP) is an anticancer medication that is commonly used to treat solid tumors. Its
use is, however, dose-restricted due to nephrotoxicity. We planned to compare the …
use is, however, dose-restricted due to nephrotoxicity. We planned to compare the …
The prospective application of melatonin in treating epigenetic dysfunctional diseases
SM Monayo, X Liu - Frontiers in Pharmacology, 2022 - frontiersin.org
In the past, different human disorders were described by scientists from the perspective of
either environmental factors or just by genetically related mechanisms. The rise in …
either environmental factors or just by genetically related mechanisms. The rise in …