Neurohormones similar to those of mammals are carried in fish by hypothalamic nerve fibers
to regulate directly follicle-stimulating hormone (FSH) and luteinizing hormone (LH) …

The transforming growth factor-β (TGF-β) superfamily contains a variety of growth factors
which all share common sequence elements and structural motifs. These proteins are …

Myostatin is a member of the TGF-β family that functions as a negative regulator of skeletal
muscle development and growth in mammals. Recently, Myostatin has also been identified …

Transplanted Spemann's organizer induces dorsal embryonic cell fates such as the nervous
system and somites, but in normal development, elimination of individual organizer signals …

The development of the vertebrate head is a highly complex process involving tissues
derived from all three germ layers. The endoderm forms pharyngeal pouches, the paraxial …

The segmentation of the vertebrate hindbrain into rhombomeres is highly conserved, but
how early hindbrain patterning is established is not well understood. We show that …

▪ Abstract The formation of the vertebrate nervous system is initiated at gastrula stages of
development, when signals from a specialized cluster of cells (the organizer) trigger neural …

Formation of the adenohypophysis in mammalian embryos occurs via an invagination of the
oral ectoderm to form Rathke's pouch, which becomes exposed to opposing dorsoventral …

Signaling by members of the TGFβ superfamily is thought to be transduced by Smad
proteins. Here, we describe a zebrafish mutant in smad5, designated somitabun (sbn). The …

The study of blood has often defined paradigms that are relevant to the biology of other
vertebrate organ systems. As examples, stem cell physiology and the structure of the …