Сalixresorcine cavitands bearing lipophilic cationic fragments in the construction of mitochondrial-targeting supramolecular nanoparticles
JE Morozova, CR Myaldzina, AD Voloshina… - Colloids and Surfaces A …, 2022 - Elsevier
The development of mitochondrial-targeting therapeutic nanoparticles is one of the crucial
tasks of nanotechnology and nanomedicine. Here the study of supramolecular macrocycles …
tasks of nanotechnology and nanomedicine. Here the study of supramolecular macrocycles …
Roles of mitochondria in oral squamous cell carcinoma therapy: Friend or foe?
J Bai, L Wu, X Wang, Y Wang, Z Shang, E Jiang… - Cancers, 2022 - mdpi.com
Simple Summary Although many therapies have been applied in oral squamous cell
carcinoma, these therapies are still unsatisfactory. Recently, the mitochondrial role in oral …
carcinoma, these therapies are still unsatisfactory. Recently, the mitochondrial role in oral …
Mitochondria-targeting polymer micelles in stepwise response releasing gemcitabine and destroying the mitochondria and nucleus for combined antitumor …
S Zhang, F Zheng, K Liu, S Liu, T Xiao, Y Zhu… - International Journal of …, 2022 - mdpi.com
Mitochondrial DNA and nuclear DNA are essential genetic material which play an important
role in maintaining normal metabolism, survival, and proliferation of cells. Constructing a …
role in maintaining normal metabolism, survival, and proliferation of cells. Constructing a …
Exploiting nuclear-mitochondrial cross-talk in theranostics: enhancing drug delivery and diagnostic precision
D Singh - Mitochondrion, 2024 - Elsevier
The dynamic interplay between nuclear and mitochondrial processes plays a pivotal role in
cellular homeostasis and disease progression. Exploiting this nuclear-mitochondrial cross …
cellular homeostasis and disease progression. Exploiting this nuclear-mitochondrial cross …
Evaluation of Anticancer Activity of 1,3‐Oxazol‐4‐ylphosphonium Salts in Vitro
Abstract A novel series of 1, 3‐oxazol‐4‐yltriphenylphosphonium salts has been
synthesized and functionalized. Oxazole derivatives were subjected to NCI in vitro …
synthesized and functionalized. Oxazole derivatives were subjected to NCI in vitro …
Circumventing challenges in mitochondrial targeting for cancer treatment: leveraging nanoplatforms for effective solutions
Cancer is a highly complex disease that affects lives and causes millions of deaths
worldwide. Several approaches are currently employed as cancer treatment options. Among …
worldwide. Several approaches are currently employed as cancer treatment options. Among …
TPP-based conjugates: potential targeting ligands
Highlights•In this review, the pivotal role of triphenylphosphonium (TPP) and its conjugates
have been widely explored.•The mechanistic insights of TPP-based conjugates endowing …
have been widely explored.•The mechanistic insights of TPP-based conjugates endowing …
Boron nanoparticles in chemotherapy and radiotherapy: the synthesis, state-of-the-art, and prospects
SA Uspenskii, PA Khaptakhanova - Russian Chemical Bulletin, 2022 - Springer
Boron neutron capture therapy (BNCT) is a radiotherapy method for cancer treatment based
on the nuclear reaction of the stable 10B isotope with epithermal neutrons that produces …
on the nuclear reaction of the stable 10B isotope with epithermal neutrons that produces …
Novel triphenylphosphonium amphiphilic conjugates of glycerolipid type: Synthesis, cytotoxic and antibacterial activity, and targeted cancer cell delivery
OV Tsepaeva, AV Nemtarev, TN Pashirova… - RSC Medicinal …, 2023 - pubs.rsc.org
This work deals with the creation of new cationic triphenylphosphonium amphiphilic
conjugates of glycerolipid type (TPP-conjugates), bearing a pharmacophore terpenoid …
conjugates of glycerolipid type (TPP-conjugates), bearing a pharmacophore terpenoid …
Aggregation-Induced Emission Luminogens for Enhanced Photodynamic Therapy: From Organelle Targeting to Tumor Targeting
Photodynamic therapy (PDT) has attracted much attention in the field of anticancer
treatment. However, PDT has to face challenges, such as aggregation caused by quenching …
treatment. However, PDT has to face challenges, such as aggregation caused by quenching …